Pumping cassette

• US 8,888,470 B2
• Filed: 10/12/2007
• Issued: 11/18/2014
• Est. Priority Date: 02/27/2007
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Demers, Jason A., Wilt, Michael J., Grant, Kevin L., Dale, James D., Tracey, Brian
• Primary Examiner(s): Freay, Charles
• Assistant Examiner(s): BOBISH, CHRISTOPHER S
• Application Number:
  US11/871,793
• Publication Number:
  US 20080253912A1
• Time in Patent Office: 2,594 Days
• Field of Search: 417/394, 417/395, 417/413.1, 417/477.2, 92/96, 92/98.R, 92/89, 604/141
• US Class Current: 417/395
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1639 linked by membranes
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1664 with temperature control
• CPC Class Codes: A61M 1/1666 by dissolving solids
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/268 the displacement member being flexible, e.g. membranes, diaphragms or bladders
• CPC Class Codes: A61M 60/37 Haemodialysis, haemofiltration or diafiltration
• CPC Class Codes: A61M 60/427 : the force acting on the blood contacting member being hydraulic or pneumatic
• CPC Class Codes: A61M 60/43 : using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/837 : Aspects of flexible displacement members, e.g. shapes or materials
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/849 : Disposable parts
• CPC Class Codes: A61M 60/851 : Valves
• CPC Class Codes: A61M 60/892 : Active valves, i.e. actuated by an external force
• CPC Class Codes: A61M 60/894 : Passive valves, i.e. valves actuated by the blood
• CPC Class Codes: F04B 13/02 : of two or more fluids at the same time
• CPC Class Codes: F04B 23/06 : the pumps being all of reciprocating positive-displacement type
• CPC Class Codes: F04B 41/06 : Combinations of two or more pumps
• CPC Class Codes: F04B 43/00 : Machines, pumps, or pumping installations having flexible working members pumps or pumping installations specially adapted for elastic fluids F04B45/00
• CPC Class Codes: F04B 43/026 : each plate-like pumping flexible member working in its own pumping chamber
• CPC Class Codes: F04B 43/06 : Pumps having fluid drive
• CPC Class Codes: F04B 43/0736 : with two or more pumping chambers in parallel
• CPC Class Codes: F04B 45/02 : having bellows
• CPC Class Codes: F04B 45/0536 : the actuating fluid being controlled by one or more valves
• CPC Class Codes: F04B 49/02 : Stopping, starting, unloading or idling control
• CPC Class Codes: F04B 49/22 : by means of valves F04B49/03 takes precedence
• CPC Class Codes: F04B 53/06 : Venting
• CPC Class Codes: F04B 53/10 : Valves; Arrangement of valves
• CPC Class Codes: F04B 53/16 : Casings; Cylinders; Cylinder liners or heads; Fluid connections
• CPC Class Codes: F04B 7/02 : the valving being fluid-actuated
• CPC Class Codes: F04B 9/109 : having plural pumping chambers
• CPC Class Codes: F17D 3/00 : Arrangements for supervising or controlling working operations
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
• CPC Class Codes: Y10T 137/0324 : With control of flow by a condition or characteristic of a fluid
• CPC Class Codes: Y10T 137/0379 : By fluid pressure
• CPC Class Codes: Y10T 137/2521 : Flow comparison or differential response
• CPC Class Codes: Y10T 137/85978 : With pump
• CPC Class Codes: Y10T 137/86139 : Serial

Abstract

A pumping cassette, the cassette includes a housing. The housing includes at least one fluid port and at least one air vent port. The air vent port vents a fluid source outside the housing. The pumping cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pump pumps fluid.

Claims

1. A pumping cassette comprising:

a housing comprising at least one membrane pump for pumping liquid, the membrane pump comprising a pumping chamber and an actuation chamber that is separated from the pumping chamber by a flexible membrane, the pumping chamber comprising at least two flowpaths for the inflow or outflow of liquid;

a first liquid port on the housing, the first liquid port being in fluid communication via one or more pump valves in the housing with one or more ports of the pumping chamber; and

a venting port on the housing, the venting port being in fluid communication via a vent valve in the housing with a vent on the housing, wherein

the venting port, vent valve and vent are fluidically isolated from the first liquid port, the one or more pump valves, and the pumping chamber of the pump, and the first liquid port and the venting port are adapted to make separate fluid connections with a reservoir external to the pumping cassette, and wherein

the first liquid port is configured to receive liquid from the reservoir, and the venting port is configured to make a venting connection with the reservoir.

2. The pumping cassette of claim 1, wherein the one or more pump valves and the vent valve are membrane valves.

3. The pumping cassette of claim 2, wherein each membrane valve comprises a liquid flow chamber separated from an actuation chamber by a flexible membrane.

4. The pumping cassette of claim 3, wherein the liquid flow chamber has at least two ports for the inflow or outflow of liquid.

5. The pumping cassette of claim 4, wherein the actuation chambers of the membrane pump and valves each comprise at least one actuation port, the at least one actuation port being configured for connection to a fluid source for actuating the membrane pump and the valves.

6. The pumping cassette of claim 5, wherein the fluid source is a source of pneumatic pressure or vacuum.

7. The pumping cassette of claim 1, wherein the one or more pump valves is a check valve.

8. The pumping cassette of claim 1, further comprising a secondary liquid flowpath fluidically isolated from the first liquid port, the one or more pump valves, and the pumping chamber of the pump, the secondary liquid flowpath comprising a second liquid port on the housing, the second liquid port being in fluid communication via a secondary valve in the housing with a third liquid port on the housing, wherein the second liquid port is adapted to make a fluid connection with the reservoir.

9. The pumping cassette of claim 8, wherein the second liquid port is configured to transfer fluid to the reservoir.

10. A system for transferring liquid to or from a reservoir, the system comprising:

a pumping cassette comprising at least one membrane pump for pumping liquid, the membrane pump comprising a pumping chamber and an actuation chamber that is separated from the pumping chamber by a flexible membrane, the pumping chamber comprising at least two flowpaths for the inflow or outflow of liquid;

a first liquid port on the cassette, the first liquid port being in fluid communication via one or more pump valves in the cassette with the one or more flowpaths of the pumping chamber; and

a first gas flow port on the cassette configured for the flow of a fluid comprising a gas through the first gas flow port, the first gas flow port being in fluid communication via a gas flow valve in the cassette with a second gas flow port on the cassette; and

a controller for controlling the actuation of the at least one membrane pump and the valves, wherein

the first and second gas flow ports and the gas flow valve are fluidically isolated from the first liquid port, the one or more pump valves and the pumping chamber of the pump so that a flowpath between the first gas flow port and the second gas flow port is separate from a flowpath associated with the first liquid port, and the controller is configured to control the inflow of liquid into the cassette via the first liquid port, and to control the flow of the fluid comprising a gas through the flowpath between the first gas flow port and the second gas flow port via the gas flow valve, wherein

the controller is configured to control the flow of liquid from a reservoir external to the cassette into the pumping chamber of the at least one membrane pump via a fluid connection between the reservoir and the first liquid port, and the controller is configured to control venting of the reservoir via a separate fluid connection between the reservoir and at least one of the first and second gas flow ports.

11. The system of claim 10, wherein the one or more pump valves and the vent valve are membrane valves.

12. The system of claim 11, wherein each membrane valve comprises a liquid flow chamber separated from an actuation chamber by a flexible membrane.

13. The system of claim 12, wherein the liquid flow chamber has at least two ports for the inflow or outflow of liquid.

14. The system of claim 13, wherein the actuation chambers of the membrane pump and valves each comprises at least one actuation port, the actuation ports being configured for connection to a fluid source for actuating the membrane pump and the valves.

15. The system of claim 14, wherein the fluid source is a source of pneumatic pressure or vacuum.

16. The system of claim 10, wherein the one or more pump valves is a check valve.

17. The system of claim 10, further comprising a secondary liquid flowpath fluidically isolated from the first liquid port, the one or more pump valves, and the pumping chamber of the pump, the secondary liquid flowpath comprising a second liquid port on the cassette, the second liquid port being in fluid communication via a secondary valve in the cassette with a third liquid port on the cassette, wherein the controller is configured to control actuation of the secondary valve.

18. The system of claim 17, wherein the controller is configured to control the flow of liquid to the reservoir via a fluid connection between the reservoir and the second liquid port on the cassette.