Functional imaging

• US 8,897,518 B2
• Filed: 02/09/2010
• Issued: 11/25/2014
• Est. Priority Date: 03/19/2009
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Solf, Torsten, Schweizer, Bernd, Weibrecht, Martin, Ribbing, Carolina
• Primary Examiner(s): Carter, Aaron W
• Application Number:
  US13/202,840
• Publication Number:
  US 20110299747A1
• Time in Patent Office: 1,750 Days
• Field of Search: 382128-132
• US Class Current: 382/128
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 6/00 Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment instruments measuring radiation intensity for application in the field of nuclear medicine, e.g. in vivo counting, G01T1/161; apparatus for taking X-ray photographs G03B42/02
• CPC Class Codes: A61B 6/037 Emission tomography
• CPC Class Codes: A61B 6/463 characterised by displaying multiple images or images and diagnostic data on one display
• CPC Class Codes: A61B 6/545 involving automatic set-up of acquisition parameters
• CPC Class Codes: A61B 8/463 characterised by displaying multiple images or images and diagnostic data on one display composite display in devices for short-range imaging with acoustic waves G01S7/52074
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039
• CPC Class Codes: A61B 8/585 Automatic set-up of the device
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS

Abstract

A method includes obtaining an image of a region of interest of a subject, wherein the image is generated with image data produced by an imaging system used to scan the subject, obtaining a signal indicative of a physiological state of the subject before the scan, and displaying both the image and data indicative of the physiological state. In another aspect, a method includes correcting, via a processor, a tracer uptake value for a target region of interest based on a tracer uptake correction factor.

Claims

1. A method, comprising:

obtaining an image of a region of interest of a subject which contrasts a tracer uptake, wherein the image is generated with image data produced by an imaging system used to scan the subject;

obtaining a signal indicative of a physiological state of the subject before the scan and the physiological state impacts the tracer uptake before the scan;

determining an expected value of the tracer uptake for the region of interest;

determining a tracer uptake correction factor based on the physiological state before the scan; and

correcting the expected value of the tracer uptake for the region of interest based on the tracer uptake correction factor; and

concurrently displaying, via a display monitor, both the image and data indicative of the physiological state.

2. The method of claim 1, further comprising annotating the image with the physiological state.

3. The method of claim 1, wherein the physiological state is one of a heart rate, a respiratory rate, a body temperature, or a glucose level.

4. The method of claim 1, further comprising:

generating supplemental data based on the signal; and

displaying the supplemental data with the image.

5. The method of claim 4, wherein the supplemental data includes a message indicating a change in value of the physiological state, relative to a baseline value, that is greater than a predetermined threshold value.

6. The method of claim 4, further comprising overlaying the supplemental data on the image.

7. The method of claim 1, further comprising adapting or changing a planned scan protocol for the scan based on the signal indicative of a physiological state.

8. The method of claim 1, further comprising:

generating a correction for the image or the image data based on the signal indicative of a physiological state; and

correcting the image or the image data based on the correction.

9. The method of claim 8, wherein the correction is based on an expected affect of the physiological state on the image data or the image.

10. The method of claim 1, further comprising:

obtaining a second signal indicative of a behavioral state of the subject before the scan and the behavioral state includes at least one of coughing, walking, consuming a beverage, an emotional state, and consuming food; and

displaying second data indicative of the behavioral state with the image, and the second data impact the contrast of the image.

11. A system, comprising:

a data packager, implemented by a configured hardware processor, that packages an image of a region of interest of a subject and data indicative of a physiological state and a behavioral state of the subject together, wherein the image is generated with image data produced by an imaging system used to scan the subject and the physiological state and the behavioral state are obtained prior to scanning the subject; and

a physiological state monitoring apparatus that includes at least one physiological monitor that determines the physiological state of the subject prior to the scan and the physiological state is used to correct an expected tracer uptake contrasted in the image.

12. The system of claim 11, wherein the data packager overlays the data indicative of the physiological state and the behavioral state of the subject on the image.

13. The system of claim 11, further comprising:

a behavioral state monitoring apparatus that includes at least one behavior monitor that determines the behavioral state of the subject prior to the scan based on at least one of answers to a questionnaire, and an observation of patient external movement, and the behavioral state impacts a tracer uptake contrasted in the image.

14. The system of claim 11, further comprising:

a supplemental information identifier, implemented by the configured hardware processor, that identifies supplemental information based on the physiological state and the behavioral state, wherein the data packager packages the supplemental information with the image.

15. The system of claim 14, wherein the supplemental information identifier identifies the supplemental information by mapping the physiological state and the behavioral state to predetermined information in a supplemental information bank.

16. The system of claim 11, further comprising:

a protocol analyzer, implemented by the configured hardware processor, that determines a modification to a scan protocol for the scan or an alternative scan protocol for the scan based on a planned scan protocol and the physiological state and the behavioral state.

17. The system of claim 11, further comprising:

a data corrector, implemented by the configured hardware processor, that determines an image or image data correction based on a planned protocol and the physiological state and the behavioral state and corrects the image or the image data based on the correction.

18. The system of claim 11 wherein the physiological or behavioral state includes state information obtained after administration of a tracer and prior to the scan and the state information changes expected values of an uptake of the tracer in the subject.

19. The system of claim 18, wherein the physiological or behavioral state includes state information obtained prior to administration of the tracer to the subject and the state information changes expected values of an uptake of the tracer in the subject.

20. A method, comprising:

obtaining a signal indicative of a physiological state and a behavioral state of a subject before a scan of the subject;

generating supplemental data indicative of an affect of the physiological state and the behavioral state on an expected tracer uptake in the subject state based on the signal; and

displaying an image concurrently with the supplemental data.