Immunoglobulin formulation and method of preparation thereof

  • US 8,900,577 B2
  • Filed: 09/06/2012
  • Issued: 12/02/2014
  • Est. Priority Date: 02/10/2003
  • Status: Active Grant
First Claim
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1. A stable, aqueous pharmaceutical formulation comprising from about 20 mg/ml to about 150 mg/ml of natalizumab, polysorbate 80 present in an amount of about 0.001% to 2% (w/v), about 10 mM phosphate buffer, and about 140 mM NaCl.

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