Multi-function optical probe system for medical and veterinary applications

• US 8,903,475 B2
• Filed: 03/05/2010
• Issued: 12/02/2014
• Est. Priority Date: 03/08/2009
• Status: Expired due to Fees

• Current Assignee: OPROBE, LLC
• Original Assignee: OPROBE, LLC
• Inventors: Brennan, Jeffrey, Humayun, Mark, Caffey, Sean
• Primary Examiner(s): REMALY, MARK DONALD
• Application Number:
  US12/718,186
• Publication Number:
  US 20100228238A1
• Time in Patent Office: 1,733 Days
• Field of Search: 356246-255, 356/479, 600/407, 600476-480
• US Class Current: 600/476
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 2017/00207 with hand gesture control or hand gesture recognition
• CPC Class Codes: A61B 2017/00694 with means correcting for movement of or for synchronisation with the body
• CPC Class Codes: A61B 2034/2048 using an accelerometer or inertia sensor
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2090/061 for measuring dimensions, e.g. length
• CPC Class Codes: A61B 2090/3735 Optical coherence tomography [OCT]
• CPC Class Codes: A61B 2090/3954 magnetic, e.g. NMR or MRI
• CPC Class Codes: A61B 3/0008 provided with illuminating means A61B3/117 takes precedence; goniolenses used for laser treatment A61F9/009; illuminating means for optical instruments G02B27/00
• CPC Class Codes: A61B 3/10 Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
• CPC Class Codes: A61B 3/102 for optical coherence tomography [OCT]
• CPC Class Codes: A61B 3/14 Arrangements specially adapted for eye photography apparatus or arrangements for taking photographs per se G03B
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/0073 by tomography, i.e. reconstruction of 3D images from 2D projections A61B5/0066 takes precedence
• CPC Class Codes: A61B 5/415 the glands, e.g. tonsils, adenoids or thymus
• CPC Class Codes: A61B 5/418 lymph vessels, ducts or nodes
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4245 involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient
• CPC Class Codes: A61B 8/5276 : due to motion
• CPC Class Codes: A61M 2025/0166 : Sensors, electrodes or the like for guiding the catheter to a target zone, e.g. image guided or magnetically guided
• CPC Class Codes: A61M 25/01 : Introducing, guiding, advancing, emplacing or holding catheters A61M25/10 takes precedence
• CPC Class Codes: A61N 5/00 : Radiation therapy ultrasound therapy A61N7/00; devices or apparatus applicable to both therapy and diagnosis A61B6/00
• CPC Class Codes: Y10T 29/49826 : Assembling or joining

Abstract

A device includes a handpiece having a probe tip disposed at an end thereof, and, connected to the handpiece such that, at the probe tip, a functionality of each is provided, a plurality of probes. The probes may include an optical coherence tomography (OCT) probe, an endoillumination probe, a laser therapy probe, an ultrasound imaging probe, an electrocautery probe, an RF ablation probe, a cryosurgical probe, an irrigator, and/or a mechanical probe.

Claims

1. An imaging system providing endoillumination and OCT probe functionalities via a single optical fiber, the system comprising:

a handpiece having a probe tip disposed at an end thereof;

disposed within the handpiece, a plurality of distinct parallel waveguides provided within a single optical fiber terminating within the probe tip; and

a plurality of light sources, a first one of the light sources being optically coupled only to a first one of the waveguides of the fiber at a proximal end thereof and a second one of the light sources being optically coupled only to a second one of the waveguides of the fiber at the proximal end, light from the first light source being propagated from the proximal end to the probe tip in the first waveguide and light from the second light source being propagated from the proximal end to the probe tip in the second waveguide such that, at the probe tip, a plurality of different probe functionalities are provided; and

driver hardware for controlling the endoillumination and OCT probe functionalities,

wherein the first and second light sources provide the endoillumination and OCT probe functionalities, respectively.

2. The device of claim 1, wherein the probe tip comprises a rotatable outer needle and, disposed at least partially within the outer needle, a rotatable inner needle.

3. The device of claim 2, wherein the probe tip comprises a non-rotatable outer sleeve disposed around the outer needle.

4. The device of claim 1, wherein the plurality of probe functionalities further comprises a laser therapy probe functionality.

5. The device of claim 1, wherein the first light source is a white-light source.

6. The device of claim 5, wherein the white-light source emits non-coherent light.

7. The device of claim 1, wherein the first light source comprises a laser light source and is coupled to the first waveguide, the second waveguide being doped so as to emit white light when excited by the laser light source.

8. The device of claim 1, wherein the first light source discrete sources of red, blue, and green light.

9. The device of claim 8, wherein each of the discrete sources of red, blue, and green light comprises a laser, the optical fiber emitting substantially white light at the probe tip.

10. The device of claim 8, wherein each of the discrete sources of red, blue, and green light is individually controllable, thereby controlling a wavelength of light emitted from the optical fiber at the probe tip.

11. The device of claim 1, further comprising disposed within the probe tip, an OCT lens assembly.

12. The device of claim 1, wherein the optical fiber is coupled to the handpiece with a fiber-optic rotary joint.

13. The device of claim 1, wherein the optical fiber is disposed within a stationary needle or sleeve coupled to the handpiece.

14. The device of claim 1, wherein the first light source comprises a white light source that is at least partially disposed within the handpiece.

15. The device of claim 14, wherein the white light source comprises one or more light-emitting diodes.

16. The device of claim 1, wherein the plurality of light sources comprises a narrow-wavelength light source providing laser therapy probe functionality at the probe tip.

17. The device of claim 16, wherein the laser therapy probe functionality comprises functionality for photocoagulation or tissue ablation.

18. The device of claim 1, wherein the driver hardware has selectable modes, each mode corresponding to one of the probe functionalities.

19. The device of claim 1, further comprising, associated with each of the waveguides, a lens disposed within the handpiece.

20. The device of claim 1, wherein the driver hardware comprises two separate drivers, one driver for controlling the OCT probe functionality and one driver for controlling the endoillumination probe functionality.

21. The device of claim 1, wherein the driver hardware comprises a single driver having selectable modes comprising a mode for controlling the OCT probe functionality and a mode for controlling the endoillumination probe functionality, the driver being configured to switch among the modes at a user'"'"'s direction.

22. The device of claim 1, wherein the fiber comprises a core and at least one cladding, the first waveguide corresponding to the at least one cladding and the second waveguide corresponding to one of the core.

23. The device of claim 1, wherein the fiber comprises a double-clad fiber, an intermediate cladding providing the first waveguide and a core of the fiber providing the second waveguide.

24. The device of claim 23, wherein the first light source is a laser light source coupled to the intermediate cladding, the core being doped so as to emit white light when excited by the laser light source.

25. The device of claim 1, wherein the fiber comprises a photonic-crystal fiber.

26. The device of claim 1, wherein the first and second light sources are coupled to the first and second waveguides via separate optical fibers.

27. A method of forming a device, the method comprising:

providing a handpiece having a probe tip disposed at an end thereof;

disposing an optical fiber comprising a plurality of distinct parallel waveguides within the handpiece such that the fiber terminates at an output facet within the probe tip; and

optically coupling a first of light source only to a first one of the multiple waveguides of the fiber at a proximal end thereof and optically coupling a second light source only to a second one of the waveguides of the fiber at the proximal end so as to provide at the probe tip, via different light outputs at the output facet, a plurality of different probe functionalities comprising an optical coherence tomography (OCT) probe functionality and an endoillumination probe functionality.