Ion imbalance detector
First Claim
Patent Images
1. A system comprising:
- a pulse generator configured to generate an electrical stimulation;
an electrode configured to deliver the electrical stimulation to a tissue in a patient;
a sensor configured to detect a mechanical response of the tissue to the electrical stimulation; and
a processor configured to determine a concentration of ions in extracellular fluid of the patient as a function of the response.
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Abstract
In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.
86 Citations
40 Claims
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1. A system comprising:
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a pulse generator configured to generate an electrical stimulation; an electrode configured to deliver the electrical stimulation to a tissue in a patient; a sensor configured to detect a mechanical response of the tissue to the electrical stimulation; and a processor configured to determine a concentration of ions in extracellular fluid of the patient as a function of the response. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method comprising:
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delivering an electrical stimulation to a tissue in a patient; detecting a response of the tissue to the electrical stimulation; and determining a concentration of ions in extracellular fluid of the patient as a function of the response, wherein the tissue is at least one of skeletal muscle, smooth muscle, cardiac muscle, nerve tissue, or skin. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A non-transitory computer-readable medium comprising instructions that cause a programmable processor to:
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control a pulse generator to deliver an electrical stimulation to a tissue in a patient; receive from a sensor a signal indicative of a mechanical response of the tissue to the electrical stimulation; and determine a concentration of ions in extracellular fluid of the patient as a function of the response. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36)
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37. A system comprising:
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means for delivering an electrical stimulation to a tissue in a patient; means for detecting a response of the tissue to the electrical stimulation; and means for determining a concentration of ions in extracellular fluid of the patient as a function of the response, wherein the tissue comprises at least one of skeletal muscle, smooth muscle, cardiac muscle, nerve tissue, and skin. - View Dependent Claims (38, 39)
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40. A method comprising:
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delivering an electrical stimulation to a tissue in a patient; detecting a mechanical response of the tissue to the electrical stimulation; and determining a concentration of ions in extracellular fluid of the patient as a function of the response.
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Specification