Patient data management apparatus for comparing patient data with ailment archetypes to determine correlation with established ailment biomarkers

• US 8,930,212 B2
• Filed: 09/24/2010
• Issued: 01/06/2015
• Est. Priority Date: 07/17/2009
• Status: Active Grant

• Current Assignee: Wavii, Inc. (Alphabet Inc.)
• Original Assignee: Wavii, Inc. (Alphabet Inc.)
• Inventors: Oakley, David, Robertson, Owen S., Jash, Ambarish
• Primary Examiner(s): PAULS, JOHN A
• Application Number:
  US12/889,697
• Publication Number:
  US 20110015942A1
• Time in Patent Office: 1,565 Days
• Field of Search: 705/2, 705/3, 435/7.2
• US Class Current: 705/2
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/4088 Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
• CPC Class Codes: A61B 5/6803 Head-worn items, e.g. helmets, masks, headphones or goggles
• CPC Class Codes: A61B 5/6814 Head
• CPC Class Codes: G06Q 10/10 Office automation; Time management
• CPC Class Codes: G06Q 99/00 Subject matter not provided for in other groups of this subclass
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: G16H 70/60 relating to pathologies

Abstract

The Medical Diagnostic Apparatus implements a physician-operated medical data analysis system for assisting a physician in identifying ailments and conditions which correlate to anomalies identified in a set of patient medical data relating to an identified patient. This system includes a plurality of biomarkers which relate to interpreting patient medical data and possible ailments associated with patient medical data. A data characterization module displays biomarkers selected by a physician and a set of patient medical data, collected from and about an identified patient, to compare the set of patient medical data with biomarkers of known ailments to enable the physician to identify an ailment representative of the patient medical data.

Claims

1. A physician operated medical data analysis system for assisting a physician in identifying ailments and conditions which correlate to anomalies identified in a set of medical data relating to an identified patient, comprising:

a physician terminal device for providing a physician with a user interface;

a memory for storing at least one set of patient medical data relating to an identified patient, which patient medical data comprises a plurality of measurements of biomarkers that correspond to a biological property of one or more organisms in the patient;

an analysis server, communicatively connected to the physician terminal device and the memory, for storing;

a plurality of sets of ailment specific biomarkers, each of which correspond to a set of characteristic biological properties that can be detected and measured in a patient, and each of which are indicative that an organism is afflicted with a predetermined ailment;

a patient data manipulation module, responsive to the physician selecting a plurality of sets of ailment specific biomarkers via the physician terminal device, configured to identify patient medical data of the identified patient that correlates with each of the biomarkers in each of the selected sets of ailment specific biomarkers; and

a data acquisition and display module for displaying on the physician terminal device for visual comparison, a visualization of each of the plurality of sets of ailment specific biomarkers selected by the physician and a visualization of the identified patient medical data of the identified patient.

2. The medical data analysis system of claim 1, further comprising:

data relations search process, responsive to a physician identified ailment, for identifying published literature in a Digital Library, which contains a plurality of published literature which relate to interpreting patient medical data and possible ailments associated with said identified patient medical data, to identify published literature associated with said physician identified ailment.

3. The medical data analysis system of claim 1 wherein said patient data manipulation module comprises:

a statistical analyzer for comparing said identified patient medical data to a set of physician selected demographic-matched reference control data.

4. The medical data analysis system of claim 3 wherein said patient data manipulation module further comprises:

an ailment identifier for generating data which identifies at least one ailment that corresponds to a variation of said identified patient medical data from said physician selected demographic-matched reference control data.

5. The medical data analysis system of claim 4 wherein said patient data manipulation module further comprises:

an ailment correlator for identifying published literature relating to said identified at least one ailment.

6. The medical data analysis system of claim 3 wherein said patient data manipulation module further comprises:

an ailment filter, responsive to data received from said physician indicative of at least one known ailment, for activating said statistical analyzer to select demographic-matched reference control data relating to said at least one known ailment.

7. The medical data analysis system of claim 3 wherein said patient data manipulation module comprises:

a predictive analyzer, responsive to said identified patient medical data, for using at least one of correlative databases, predictive databases, and trait indices to generate an estimation of a likelihood that said identified patient will develop particular ailments.

8. The medical data analysis system of claim 7 wherein said patient data manipulation module comprises:

an ailment correlator, responsive to said predictive analyzer generating an estimation of a likelihood that said identified patient will develop particular ailments, for identifying published literature relating to said particular ailments.

9. The medical data analysis system of claim 1 wherein said set of patient medical data comprises:

monitoring data collected from medical devices operable to measure physiological data relating to said identified patient.

10. A method of operating a physician-operated medical data analysis system for assisting a physician in identifying ailments and conditions which correlate to anomalies identified in a set of patient medical data relating to an identified patient, comprising:

providing a physician terminal device;

storing in a memory at least one set of patient medical data relating to an identified patient, which patient medical data comprises a plurality of measurements of biomarkers that correspond to a biological property of one or more organisms in the patient;

storing, in a memory, a plurality of sets of ailment specific biomarkers each of which correspond to a set of characteristic biological properties that can be detected and measured in a patient, and each of which are indicative that an organism is afflicted with a predetermined ailment;

identifying, in response to the physician selecting a plurality of sets of ailment specific biomarkers via the physician terminal device, patient medical data of the identified patient that correlates with each of the biomarkers in each of the selected sets of ailment specific biomarkers; and

displaying, on the physician terminal device for visual comparison, a visualization of each of the plurality of sets of ailment specific biomarkers selected by the physician and a visualization of the identified patient medical data of the identified patient.

11. The method of operating a medical data analysis system of claim 10, further comprising:

identifying, in response to a physician-identified ailment, published literature in a Digital Library, which contains a plurality of published literature which relate to interpreting patient medical data and possible ailments associated with said identified patient medical data, to identify published literature associated with said physician identified ailment.

12. The method of operating a medical data analysis system of claim 10 wherein said step of displaying comprises:

comparing said identified patient medical data to a set of physician-selected demographic-matched reference control data.

13. The method of operating a medical data analysis system of claim 12 wherein said step of displaying further comprises:

generating data which identifies at least one ailment that corresponds to a variation of said identified patient medical data from said physician-selected demographic-matched reference control data.

14. The method of operating a medical data analysis system of claim 13 wherein said step of displaying further comprises:

identifying published literature relating to said identified ailments.

15. The method of operating a medical data analysis system of claim 12 wherein said step of displaying further comprises:

activating, in response to data received from said physician indicative of at least one known ailment, said statistical analyzer to select demographic-matched reference control data relating to said at least one known ailment.

16. The method of operating a medical data analysis system of claim 12 wherein said step of displaying comprises:

using, in response to said identified patient medical data, at least one of correlative databases, predictive databases, and trait indices to generate an estimation of a likelihood that said identified patient will develop particular ailments.

17. The method of operating a medical data analysis system of claim 16 wherein said step of displaying comprises:

identifying, in response to said step of generating an estimation of a likelihood that said identified patient will develop particular ailments, published literature relating to said particular ailments.

18. The method of operating a medical data analysis system of claim 10 wherein said set of patient medical data comprises:

monitoring data collected from medical devices operable to measure physiological data relating to said identified patient.