Diaphragm pump and pumping systems

• US 8,932,032 B2
• Filed: 05/15/2012
• Issued: 01/13/2015
• Est. Priority Date: 07/13/2005
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius Medical Care AG)
• Inventors: Orr, Troy J.
• Primary Examiner(s): LETTMAN, BRYAN MATTHEW
• Application Number:
  US13/472,099
• Publication Number:
  US 20120224984A1
• Time in Patent Office: 973 Days
• Field of Search: 417/413.1, 417/322, 417/394, 417/395, 417/507, 417/521, 417/533, 92/48, 92/49, 92/96, 92/98.R, 137/512.15, 137/512.4, 137/859, 604/6.11
• US Class Current: 417/395
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00 ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/3666 Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
• CPC Class Codes: A61M 1/3667 with assisted venous return
• CPC Class Codes: A61M 2202/0413 Blood
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 60/109 incorporated within extracorporeal blood circuits or systems
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/38 Blood oxygenation
• CPC Class Codes: A61M 60/43 using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/847 arranged in a cassette
• CPC Class Codes: A61M 60/851 Valves
• CPC Class Codes: A61N 2005/1021 Radioactive fluid
• CPC Class Codes: F04B 2201/0601 Opening times
• CPC Class Codes: F04B 2201/0605 Leakage over a valve
• CPC Class Codes: F04B 23/04 Combinations of two or more pumps
• CPC Class Codes: F04B 43/06 Pumps having fluid drive
• CPC Class Codes: F04B 43/0736 with two or more pumping chambers in parallel
• CPC Class Codes: F04B 45/043 two or more plate-like pumping flexible members in parallel
• CPC Class Codes: F04B 45/0536 the actuating fluid being controlled by one or more valves
• CPC Class Codes: F04B 53/109 inlet and outlet valve forming one unit
• CPC Class Codes: F04B 7/02 : the valving being fluid-actuated
• CPC Class Codes: F04B 7/0275 : and being deformable, e.g. membranes
• CPC Class Codes: Y10T 137/7843 : Integral resilient member forms plural valves

Abstract

A process fluid pump can include a pump chamber, an inlet valve, and an outlet valve. Diaphragm regions can define at least a portion of each of the pump chamber, the inlet valve, and the outlet valve. The diaphragm regions can each have an actuation region with a surface that is convexly shaped when the formed actuation region is in a natural unstressed first state, and each formed actuation region can be actuated by a motive fluid to transition to a second state in which the surface is non-convexly shaped.

Claims

1. A medical pump for moving a fluid of a patient to and from the patient, the pump comprising:

a first pump chamber configured to be actuated by a motive fluid;

a first inlet valve configured to actively control ingress of the fluid of the patient to the first pump chamber and a first outlet valve configured to actively control egress of the fluid of the patient from the first pump chamber;

a second pump chamber configured to be actuated by the motive fluid;

a second inlet valve configured to actively control ingress of the fluid of the patient to the second pump chamber and a second outlet valve configured to actively control egress of the fluid of the patient from the second pump chamber;

a first diaphragm region configured to isolate the motive fluid from the fluid of the patient within the first pump chamber;

a second diaphragm region configured to isolate the motive fluid from the fluid of the patient within the first inlet valve;

a third diaphragm region configured to isolate the motive fluid from the fluid of the patient within the first outlet valve;

a fourth diaphragm region configured to isolate the motive fluid from the fluid of the patient within the second pump chamber;

a fifth diaphragm region configured to isolate the motive fluid from the fluid of the patient within the second inlet valve;

a sixth diaphragm region configured to isolate the motive fluid from the fluid of the patient within the second outlet valve;

an inlet channel in fluid communication with each of the first and second inlet valves to permit fluid of the patient to flow into each of the first and second inlet valves; and

an outlet channel in fluid communication with each of the first and second outlet valves to receive fluid of the patient that flows out of the first and second outlet valves,

wherein the first, second, third, fourth, fifth, and sixth diaphragm regions comprise first, second, third, fourth, fifth, and sixth formed actuation regions, respectively, wherein each formed actuation region comprises a surface that is convexly shaped when the formed actuation region is in a natural unstressed first state, and

wherein each formed actuation region is configured to be actuated by the motive fluid to transition to a second state in which the surface is non-convexly shaped,

wherein movement of each of the first, second, third, fourth, fifth, and sixth diaphragm regions within its respective chamber or valve is achieved solely by differences in fluid pressure at opposite sides of the diaphragm region, and

wherein the first and second pump chambers are configured to be actuated independently of one another.

2. The medical pump of claim 1, wherein a first piece of diaphragm material comprises the first diaphragm region and a second piece of diaphragm material comprises the second diaphragm region.

3. The medical pump of claim 2, wherein a third piece of diaphragm material comprises the third diaphragm region.

4. The medical pump of claim 1, wherein a single piece of diaphragm material comprises the second diaphragm region and one or more of the first diaphragm region or the third diaphragm region.

5. The medical pump of claim 1, further comprising a substantially rigid first housing member and a substantially rigid second housing member,

wherein the first diaphragm region is disposed between the first and second housing members and cooperates therewith to at least partially define the first pump chamber,

wherein the second diaphragm region is disposed between the first and second housing members and cooperates therewith to at least partially define the first inlet valve,

wherein the third diaphragm region is disposed between the first and second housing members and cooperates therewith to at least partially define the first outlet valve, and

wherein the second housing member comprises a first recess that at least partially defines the first pump chamber, a second recess that at least partially defines the first inlet valve, and a third recess that at least partially defines the first outlet valve.

6. The medical pump of claim 5, wherein the second housing member comprises a first air transfer connector in fluid communication with the first pump chamber, a second air transfer connector in fluid communication with the first inlet valve, and a third air transfer connector in fluid communication with the first outlet valve, wherein the first, second, and third air transfer connectors are configured to permit motive fluid to pass through them to effect movement of the first, second, and third formed actuation regions, respectively.

7. The medical pump of claim 6, wherein each air transfer connector comprises a hollow boss that protrudes from and is integrally formed with the second housing member.

8. The medical pump of claim 7, wherein a first piece of diaphragm material comprises the first diaphragm region and a second piece of diaphragm material comprises the second diaphragm region.

9. The medical pump of claim 1, wherein the first formed actuation region that at least partially defines the first pump chamber comprises a dome shape when in the natural unstressed first state and comprises an oppositely directed dome shape when in the second state.

10. The medical pump of claim 1, wherein each formed actuation region transitions from the natural unstressed first state to the second state without substantially stretching a diaphragm material of which the formed actuation region is formed.

11. The medical pump of claim 1, wherein the first pump chamber is configured to be filled as the second pump chamber is emptied and the first pump chamber is configured to be emptied as the second pump chamber is filled.

12. The medical pump of claim 1, wherein the first and second inlet valves are configured to be actuated opposite of each other such that the first inlet valve is open when the second inlet valve is closed and the first inlet valve is closed when the second inlet valve is open, and

wherein the first and second outlet valves are configured to be actuated opposite of each other such that the first outlet valve is open when the second outlet valve is closed and such that the first outlet valve is closed when the second outlet valve is open.

13. A medical pumping system comprising:

a process fluid inlet line configured to conduct a process fluid from a patient therethrough;

a process fluid outlet line configured to conduct the process fluid therethrough; and

a medical pump that comprises;

a first pump chamber configured to be actuated by a motive fluid;

a first inlet valve configured to actively control ingress of the process fluid to the first pump chamber and a first outlet valve configured to actively control egress of the process fluid from the first pump chamber;

a second pump chamber configured to be actuated by the motive fluid;

a second inlet valve configured to actively control ingress of the process fluid to the second pump chamber and a second outlet valve configured to actively control egress of the process fluid from the second pump chamber;

a first diaphragm region configured to isolate the motive fluid from the process fluid within the first pump chamber;

a second diaphragm region configured to isolate the motive fluid from the process fluid within the first inlet valve;

a third diaphragm region configured to isolate the motive fluid from the process fluid within the first outlet valve;

a fourth diaphragm region configured to isolate the motive fluid from the process fluid within the second pump chamber;

a fifth diaphragm region configured to isolate the motive fluid from the process fluid within the second inlet valve;

a sixth diaphragm region configured to isolate the motive fluid from the process fluid within the second outlet valve;

an inlet channel in fluid communication with the process fluid inlet line and in communication with each of the first and second inlet valves to receive process fluid from the process fluid inlet line and to permit process fluid to flow into each of the first and second inlet valves; and

an outlet channel in fluid communication with the process fluid outlet line and in communication with each of the first and second outlet valves to receive process fluid that flows out of the first and second outlet valves and to conduct process fluid into the process fluid outlet line,

wherein the first, second, third, fourth, fifth, and sixth diaphragm regions comprises first, second, third, fourth, fifth, and sixth formed actuation regions, respectively, wherein each formed actuation region comprises a surface that is convexly shaped when the formed actuation region is in a natural unstressed first state, and wherein each formed actuation region is configured to be actuated by the motive fluid to transition to a second state in which the surface is non-convexly shaped,

wherein movement of each of the first, second, third, fourth, fifth, and sixth diaphragm regions within its respective chamber or valve is achieved solely by differences in fluid pressure at opposite sides of the diaphragm region, and

wherein the first and second pump chambers are configured to be actuated independently of one another.

14. The medical pumping system of claim 13, wherein the process fluid inlet line conducts the process fluid away from a process fluid source and wherein the process fluid outlet line conducts the process fluid toward a process fluid destination.

15. The medical pumping system of claim 14, wherein the fluid pumping system is a hemodialysis circuit, and wherein the process fluid comprises blood.

16. The medical pumping system of claim 15, further comprising a dialyzer through which the process fluid passes.

17. The medical pumping system of claim 13, further comprising a pump control system with which the medical pump is selectively coupled.

18. A medical pump for pumping a physiological fluid from a patient, the pump comprising:

an inlet channel for receiving the physiological fluid from the patient;

a first pump chamber and a second pump chamber, wherein each pump chamber comprises;

a pump chamber cavity that is configured to receive the physiological fluid from the inlet channel and comprises a surface;

a pump actuation cavity that comprises a surface; and

a pump diaphragm actuation region that isolates the pump chamber cavity from the pump actuation cavity, wherein the pump diaphragm actuation region is preformed to a convex shape and is configured to transition between a first end-of-stroke state and a second end-of stroke state, wherein the pump diaphragm actuation region is supported by a portion of the pump chamber cavity surface when in the first end-of-stroke state and is supported by a portion of the pump actuation cavity surface when in the second end-of-stroke state, and wherein the pump diaphragm actuation region is in the convex shape when in one of the first and second end-of-stroke states and is substantially inverted relative to the convex shape when in the other of the first and second end-of-stroke states; and

four valves, wherein each valve comprises;

a valve chamber;

a valve actuation cavity; and

a valve diaphragm actuation region that isolates the valve chamber from the valve actuation cavity,

wherein two of the valves are coupled with the first pump chamber and the other two valves are coupled with the second pump chamber.

19. The medical pump of claim 18, wherein the pump diaphragm actuation region comprises a substantially rounded dome shape when in the first end-of-stroke state and comprises an oppositely directed substantially rounded dome shape when in the second end-of-stroke state.

20. The medical pump of claim 18, wherein each pump diaphragm actuation region transitions from the first end-of-stroke state to the second end-of-stroke state without substantially stretching a diaphragm material of which the pump diaphragm actuation region is formed.

21. The medical pump of claim 18, wherein a unitary piece of diaphragm material comprises a pump diaphragm actuation region and a plurality of valve diaphragm actuation regions.

22. The medical pump of claim 18, wherein a unitary piece of diaphragm material comprises a plurality of pump diaphragm actuation regions.

23. The medical pump of claim 18, wherein a unitary piece of diaphragm material comprises a plurality of pump diaphragm actuation regions and a plurality of valve diaphragm actuation regions.

24. The medical pump of claim 18, wherein each of the pump diaphragm actuation regions is preformed to the concave shape from a material that has a uniform thickness.

25. The medical pump of claim 18, wherein the pump comprises at least one outlet channel for delivering the physiological fluid back to the patient.

26. A medical pump for pumping a physiological fluid from a patient, the pump comprising:

an inlet channel for receiving a physiological fluid from a patient;

a first pump chamber and a second pump chamber, wherein each pump chamber comprises;

a pump chamber cavity that is configured to receive the physiological fluid from the inlet channel and comprises a surface;

a pump actuation cavity that comprises a surface; and

a pump diaphragm actuation region that isolates the pump chamber cavity from the pump actuation cavity, wherein the pump diaphragm actuation region is preformed into a substantially rounded convex shape and is configured to transition between a first end-of-stroke state and a second end-of stroke state, wherein the pump diaphragm actuation region is supported by a portion of the pump chamber cavity surface when in the first end-of-stroke state and is supported by a portion of the pump actuation cavity surface when in the second end-of-stroke state, and wherein the pump diaphragm actuation region is in the substantially rounded convex shape when in one of the first and second end-of-stroke states and is substantially inverted to a substantially rounded shape when in the other of the first and second end-of-stroke states; and

four valves, wherein each valve comprises;

a valve chamber;

a valve actuation cavity; and

a valve diaphragm actuation region that isolates the valve chamber from the valve actuation cavity,

wherein two of the valves are associated with the first pump chamber and the other two valves are associated with the second pump chamber, and

wherein a unitary piece of diaphragm material comprises a plurality of pump diaphragm actuation regions.

27. The medial pump of claim 26, wherein each of the pump diaphragm actuation regions is preformed into the convex shape from a material of uniform thickness.