Assessment of sudomor function for peripheral diabetic neuropathy evaluation

  • US 8,934,954 B2
  • Filed: 08/23/2011
  • Issued: 01/13/2015
  • Est. Priority Date: 08/23/2011
  • Status: Active Grant
First Claim
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1. A method for assessing sudomotor function of a patient, with a view to diagnosing autonomic neuropathy, the method being performed in a system comprising:

  • an anode and a cathode, intended to be placed on different regions of the patient body;

    an adjustable DC source, which is controlled in order to feed the anode with a DC current;

    the method comprising the following steps;

    applying DC voltage pulses of varying voltage values in order to stress sweat glands, the voltage pulses lasting given durations allowing the stabilization of electrochemical phenomena in the body in the vicinity of the electrodes;

    collecting data representative of the current between the anode and the cathode, and of the potential generated on the cathode through reverse iontophoresis for the different DC voltages;

    from the data, computing results representative of the electrochemical skin conductance of the patient; and

    reconciling the data representative of the electrochemical skin conductance of the patient with reference data obtained in the same conditions on patients identified as suffering or not from autonomic neuropathy, and identifying the patient as suffering or not from sudomotor dysfunction.

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