Nicotine lozenge composition

  • US 8,940,772 B2
  • Filed: 06/26/2013
  • Issued: 01/27/2015
  • Est. Priority Date: 05/01/2008
  • Status: Active Grant
First Claim
Patent Images

1. An oral lozenge composition comprising:

  • a) a master granule component comprising;

    at least one an alkaline buffering agent selected from the group consisting of sodium carbonate, sodium bicarbonate, potassium phosphate, potassium carbonate and potassium bicarbonate, and mixtures thereof;

    at least one dissolution modifier; and

    at least one diluent wherein the master granule component is obtained through wet or dry granulation; and

    b) an extragranular component blended with the master granule component comprising nicotine polacrilex and at least one alkaline buffering agent selected from the group consisting of sodium carbonate, sodium bicarbonate, potassium phosphate, potassium carbonate and potassium bicarbonate, and mixtures thereof.

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