Method and apparatus for treatment of ocular tissue using combine modalities
First Claim
1. An apparatus for treatment of ocular tissue comprising:
- a laser operative at a wavelength selected from the ranges of 1.4 μ
m to 1.54μ
m or 1.8 μ
m to 6.0 μ
m for irradiating an ocular surface and inducing symmetrically uniform lesions in a subsurface region below the ocular surface to modify the shape of the ocular surface;
an ocular surface cooling mechanism configured for controlling temperature of the ocular surface irradiated by the laser; and
an ultraviolet radiation source configured to irradiate the ocular surface and the subsurface region to induce crosslinking of ocular tissue below the ocular surface in or near the lesions.
3 Assignments
0 Petitions
Accused Products
Abstract
An apparatus and a method are provided for treating a targeted area of ocular tissue in a tissue-sparing manner comprising use of two or more therapeutic modalities, including thermal radiation source (such as an CW infrared fiber laser), operative in a wavelength range that has a high absorption in water, and photochemical collagen cross-linking (CXL), together with one or more specific system improvements, such as peri-operative feedback measurements for tailoring of the therapeutic modalities, an ocular tissue surface thermal control/cooling mechanism and a source of deuterated water/riboflavin solution in a delivery system targeting ocular tissue in the presence of the ultraviolet radiation. Additional methods of rapid cross-linking (RXL), are provided that further enables cross-linking (CXL) therapy to be combined with thermal therapy.
34 Citations
10 Claims
-
1. An apparatus for treatment of ocular tissue comprising:
-
a laser operative at a wavelength selected from the ranges of 1.4 μ
m to 1.54μ
m or 1.8 μ
m to 6.0 μ
m for irradiating an ocular surface and inducing symmetrically uniform lesions in a subsurface region below the ocular surface to modify the shape of the ocular surface;an ocular surface cooling mechanism configured for controlling temperature of the ocular surface irradiated by the laser; and an ultraviolet radiation source configured to irradiate the ocular surface and the subsurface region to induce crosslinking of ocular tissue below the ocular surface in or near the lesions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification