Formulations of low dose diclofenac and beta-cyclodextrin

  • US 8,946,292 B2
  • Filed: 05/12/2011
  • Issued: 02/03/2015
  • Est. Priority Date: 03/28/2006
  • Status: Active Grant
First Claim
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1. A method of providing analgesia to a subject in need thereof, which method comprises parenterally administering to the subject a pharmaceutical composition, wherein the composition comprises:

  • (a) from about 18.75 mg to about 37.5 mg of a diclofenac compound; and

    (b) a beta-cyclodextrin compound;

    wherein the dosage of the diclofenac compound is less than about 1.3 mg/kg per day; and

    wherein the method achieves at least about 82% of maximum observable total pain relief assessed by a Visual Analog Scale.

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