Methods of treating hepatic encephalopathy

  • US 8,969,398 B2
  • Filed: 02/15/2013
  • Issued: 03/03/2015
  • Est. Priority Date: 10/02/2008
  • Status: Active Grant
First Claim
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1. A method of decreasing a subject'"'"'s risk of a hepatic encephalopathy (HE) breakthrough episode comprising administering rifaximin daily for a period of about 12 months or longer to a subject suffering from HE, thereby decreasing the subject'"'"'s risk of an HE breakthrough episode, wherein a breakthrough episode is defined as an increase of the Conn score to Grade ≧

  • 2 or an increase in Conn score of 1 and asterixis grade of 1 for subjects having a baseline Conn score of 0.

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