Prediction and monitoring of clinical episodes
First Claim
Patent Images
1. A method comprising:
- sensing a motion-related parameter of a subject without contacting or viewing the subject or clothes the subject is wearing;
deriving heartbeat- and breathing-related signals from the motion-related parameter; and
demodulating the heartbeat-related signal using the breathing-related signal.
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Abstract
Apparatus and methods are described, including a method for treating a clinical episode. The method comprises sensing at least one parameter of a subject without contacting or viewing the subject or clothes the subject is wearing, analyzing the parameter, detecting the clinical episode at least in part responsively to the analysis, and responsively to detecting the clinical episode, treating the clinical episode using a device implanted in the subject. Other applications are also described.
295 Citations
58 Claims
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1. A method comprising:
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sensing a motion-related parameter of a subject without contacting or viewing the subject or clothes the subject is wearing; deriving heartbeat- and breathing-related signals from the motion-related parameter; and demodulating the heartbeat-related signal using the breathing-related signal. - View Dependent Claims (2, 3, 4, 5)
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6. A method for treating a subject, comprising:
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sensing a motion-related parameter of a subject without contacting or viewing the subject or clothes the subject is wearing; analyzing the parameter; responsively at least in part to the analysis, determining an initial dosage of a drug for administration to the subject; and communicating the initial dosage to a drug administration device used by the subject. - View Dependent Claims (7)
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8. A method for treating a clinical episode, comprising:
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sensing at least one parameter of a subject without contacting or viewing the subject or clothes the subject is wearing; analyzing the parameter; detecting the clinical episode at least in part responsively to the analysis; and responsively to detecting the clinical episode, treating the clinical episode using a device implanted in the subject.
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9. A method comprising:
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sensing at least one parameter of a subject, using exactly one sensor placed in or under a reclining surface upon which the subject lies, which sensor does not contact the subject or clothes the subject is wearing; and detecting coughing of the subject by analyzing the parameter. - View Dependent Claims (10)
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11. A method for determining a heart rate of a subject, comprising:
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sensing a first pulse signal of the subject in a vicinity of a first location of the subject selected from;
a chest of the subject, and an abdomen of the subject, without contacting the subject or clothes the subject is wearing;sensing a second pulse signal of the subject in a vicinity of a second location of the subject anatomically below a waist of the subject, without contacting the subject or clothes the subject is wearing; and determining the heart rate responsively to the first and second pulse signals. - View Dependent Claims (12, 13, 14, 15, 16)
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17. A method comprising:
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sensing first and second motion-related parameters of a subject in a vicinity of a first site and in a vicinity of a second site of the subject, respectively, without contacting or viewing the subject or clothes the subject is wearing; deriving first and second breathing-related signals from the first and second motion-related parameters, respectively; and analyzing the first and second breathing-related signals to determine a measure of thoracoabdominal asynchrony (TAA) of the subject. - View Dependent Claims (18, 19)
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20. A method comprising:
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sensing first and second motion-related parameters of a subject in a vicinity of a first site and in a vicinity of a second site of the subject, respectively, without contacting or viewing the subject or clothes the subject is wearing; deriving first and second breathing-related signals from the first and second motion-related parameters, respectively; and analyzing the first and second breathing-related signals to determine a measure of accessory muscle activity of the subject. - View Dependent Claims (21, 22)
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23. A method for predicting an onset of a clinical episode, comprising:
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sensing at least one parameter of a subject; and while a breathing rate of the subject is less than 120% of a baseline asymptomatic breathing rate of the subject, predicting the onset of the clinical episode at least in part responsively to the sensed parameter. - View Dependent Claims (24, 25, 26, 27)
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28. A method for predicting an onset of an asthma attack, comprising:
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sensing at least one parameter of a subject; and while a forced expiratory volume in one second (FEV1) of the subject is greater than 90% of a baseline asymptomatic FEV1 of the subject, predicting the onset of the asthma attack at least in part responsively to the sensed parameter. - View Dependent Claims (29)
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30. A method for predicting an onset of a clinical episode, comprising:
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sensing at least one parameter of a subject without contacting or viewing the subject or clothes the subject is wearing; and at least one hour prior to the onset of the clinical episode, predicting the onset at least in part responsively to the sensed parameter. - View Dependent Claims (31, 32, 33, 34)
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35. A method for predicting an onset of a clinical episode, comprising:
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sensing at least one parameter of a subject substantially continuously during a period having a duration of at least one hour; and at least one hour prior to the onset of the clinical episode, predicting the onset at least in part responsively to the sensed parameter. - View Dependent Claims (36, 37, 38, 39, 40)
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41. A method for predicting an onset of a clinical episode, comprising:
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sensing at least one parameter of a subject substantially continuously during at least 80% of a period of time a subject is sleeping at night; and at least in part responsively to the sensed parameter, predicting the onset of the clinical episode at least one hour prior to the onset. - View Dependent Claims (42, 43, 44)
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45. A method comprising:
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sensing at least one parameter of a subject; and at least in part responsively to the sensed parameter, calculating a probability that a clinical episode will occur within a predetermined period of time after the calculating. - View Dependent Claims (46, 47, 48, 49, 50, 51)
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52. Apparatus for predicting an onset of a clinical episode, comprising:
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a sensor, adapted to acquire a breathing-related time-domain signal of a subject; and a control unit, adapted to; transform the time-domain signal into a frequency-domain signal, determine a breathing rate of the subject by identifying a peak in a breathing-related frequency range of the frequency-domain signal, determine one or more harmonics of the peak frequency, determine a relationship between; (a) a first energy level, selected from the list consisting of;
an energy level associated with one of the one or more harmonics, and an energy level associated with a frequency of the peak, and(b) a second energy level, associated with one of the one or more harmonics; compare the relationship with a baseline level of the relationship, and predict the onset of the episode at least in part responsively to the comparison.
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53. Apparatus for monitoring blood pressure, comprising:
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a non-contact sensor, adapted to sense a motion-related parameter of a subject without contacting the subject or clothes the subject is wearing; and a control unit, adapted to analyze the parameter to determine a measure of blood pressure of the subject.
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54. Apparatus for predicting an onset of a clinical episode, comprising:
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a sensor, adapted to sense at least one parameter of a subject; and a control unit, adapted to; analyze the parameter, receive data regarding a drug administered to the subject, and predict the onset of a clinical episode at least in part responsively to the analysis and the drug administration data in combination. - View Dependent Claims (55)
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56. Apparatus comprising:
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a non-contact sensor, adapted to sense at least one parameter of a subject while the subject sleeps, without contacting the subject or clothes the subject is wearing; and a control unit, adapted to analyze the parameter to determine a measure of restlessness of the subject.
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57. Apparatus comprising:
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a non-contact sensor, adapted to sense at least one parameter of a subject while the subject sleeps, without contacting the subject or clothes the subject is wearing; and a control unit, adapted to detect Periodic Limb Movements in Sleep (PLMS) of the subject by analyzing the parameter.
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58. Apparatus for detecting pulsus paradoxus of a subject, comprising:
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a non-contact sensor, adapted to sense at least one parameter of a subject without contacting the subject or clothes the subject is wearing; and a control unit, adapted to; analyze the parameter to generate a measure of blood pressure change of the subject over an inspiration/expiration cycle, compare the measure of blood pressure change to a threshold, and responsively to the measure being greater than the threshold, detect the pulsus paradoxus.
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Specification