Sampling plate

• US 9,011,658 B2
• Filed: 03/30/2011
• Issued: 04/21/2015
• Est. Priority Date: 03/30/2010
• Status: Active Grant

• Current Assignee: Jabil Circuit Limited (Jabil Inc.)
• Original Assignee: Jabil Circuit Limited (Jabil Inc.)
• Inventors: Bryan, Matthew Robert
• Primary Examiner(s): Van, Luan
• Assistant Examiner(s): Kessel, Maris R
• Application Number:
  US13/637,801
• Publication Number:
  US 20130026037A1
• Time in Patent Office: 1,483 Days
• Field of Search: 20440301-40315, 204/415, 422/547
• US Class Current: 204/415
• CPC Class Codes: B01L 2200/027 for microfluidic devices
• CPC Class Codes: B01L 2200/0605 Metering of fluids
• CPC Class Codes: B01L 2300/0636 Integrated biosensor, microarrays
• CPC Class Codes: B01L 2300/0822 Slides
• CPC Class Codes: B01L 2300/0825 Test strips
• CPC Class Codes: B01L 2300/0887 Laminated structure
• CPC Class Codes: B01L 3/502715 characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
• CPC Class Codes: B01L 3/502723 characterised by venting arrangements

Abstract

The present invention relates to a sampling plate. In particular the invention relates to a sampling plate for measuring certain selected properties of a liquid sample, such as the glucose levels in a blood sample. Sampling plates of the present invention have a sample zone (20) for receiving a liquid sample and an overflow reservoir (26) linked to the sample zone (20) via an overflow channel (26a), so that excess blood sample can be redirected away from the sample zone (20) and contained.

Claims

1. A sampling plate, comprising:

a sample zone for receiving a liquid sample;

an air porous body which is in fluid communication with the sample zone, the air porous body being arranged to receive air displaced from the sample zone as the liquid sample is received into the sample zone;

an overflow reservoir linked to the sample zone via an overflow channel;

a loading port for loading the liquid sample; and

a loading path between the loading port and sample zone along which the liquid sample can travel towards the sample zone;

wherein the sample zone comprises;

at least two discrete testing zones, each defined by a well, having a hydrophobic boundary lying between the at least two testing zones; and

a raised hydrophobic loading platform located towards a central region lying between all the respective testing zones, the loading platform being arranged to first receive the liquid sample before distributing the liquid sample amongst the respective testing zones;

wherein each testing zone comprises;

a hydrophilic portion; and

a pair of electrodes which is bridged, in use, by the liquid sample in a testing zone;

wherein the overflow channel is linked to the hydrophobic loading platform to enable the liquid sample to flow from the hydrophobic loading platform into the overflow reservoir;

wherein the overflow channel is discrete from the at least two discrete testing zones, and separated therefrom by a hydrophobic boundary; and

wherein the overflow channel is narrower than each respective entrance to the testing zones.

2. The sampling plate as claimed in claim 1, wherein the overflow reservoir is auxiliary to the testing zones.

3. The sampling plate as claimed in claim 2, wherein the overflow reservoir has a volume capacity exceeding the volume capacity of a single testing zone.

4. The sampling plate as claimed in claim 3, wherein the overflow reservoir has a volume capacity exceeding the total volume capacity of all the testing zones of the sample zone.

5. The sampling plate as claimed in claim 1, wherein the sample zone comprises a distribution center arranged to distribute the liquid sample to the testing zone(s), wherein the overflow channel is linked to the distribution center to enable the liquid sample to flow from the distribution center into the overflow reservoir.

6. The sampling plate as claimed in claim 1, wherein the overflow reservoir is a well.

7. The sampling plate as claimed in claim 1, wherein the overflow channel is arranged to restrict flow of the liquid sample into the overflow reservoir to a greater extent than flow is restricted into the testing zone(s).

8. The sampling plate as claimed in claim 1, wherein the overflow channel widens towards the overflow reservoir.

9. The sampling plate as claimed in claim 1, wherein the air porous body is in fluid communication with the overflow reservoir.