Transdermal electrical stimulation methods for modifying or inducing cognitive state
First Claim
1. A method of enhancing attention, alertness, or mental focus or of enhancing a calm or relaxed mental state, the method comprising:
- placing a first electrode of a portable transdermal electrical stimulation (TES) applicator on the subject'"'"'s skin on a temple region on a first side of the subject'"'"'s body;
placing a second electrode on the subject'"'"'s skin on either the mastoid region of the first side of the subject'"'"'s body or on the subject'"'"'s neck;
activating the TES applicator to deliver a pulsed, asymmetric, biphasic transdermal electrical stimulation having a frequency of 750 Hz or greater and an intensity of or greater than 5 mA; and
modifying the subject'"'"'s cognitive state by applying the biphasic transdermal electrical stimulation between the first and second electrodes for 10 seconds or longer.
4 Assignments
0 Petitions
Accused Products
Abstract
Methods of modifying a subject'"'"'s cognitive state by applying transdermal electrical stimulation (TES). In particular, described herein are methods of applying TES using a pair of electrodes each positioned at a particular location on the skin of the subject'"'"'s head, or the head and neck, to evoke a predetermined cognitive state using a TES applicator. In particular, described herein are methods of enhancing attention, alertness, or mental focus or of enhancing a calm or relaxed mental state by applying high-intensity TES across electrodes positioned on the subject'"'"'s temple and either the mastoid region or on the subject'"'"'s neck. The subject may control the application directly and TES may be applied by a portable, including wearable, TES applicator.
162 Citations
30 Claims
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1. A method of enhancing attention, alertness, or mental focus or of enhancing a calm or relaxed mental state, the method comprising:
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placing a first electrode of a portable transdermal electrical stimulation (TES) applicator on the subject'"'"'s skin on a temple region on a first side of the subject'"'"'s body; placing a second electrode on the subject'"'"'s skin on either the mastoid region of the first side of the subject'"'"'s body or on the subject'"'"'s neck; activating the TES applicator to deliver a pulsed, asymmetric, biphasic transdermal electrical stimulation having a frequency of 750 Hz or greater and an intensity of or greater than 5 mA; and modifying the subject'"'"'s cognitive state by applying the biphasic transdermal electrical stimulation between the first and second electrodes for 10 seconds or longer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of enhancing attention, alertness, or mental focus or of enhancing a calm or relaxed mental state, the method comprising:
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instructing a subject to place a first electrode of a portable transdermal electrical stimulation (TES) applicator on the subject'"'"'s skin on a temple region on a first side of the subject'"'"'s body; instructing the subject to place a second electrode on the subject'"'"'s skin on the subject'"'"'s head or neck on the first side of the subject'"'"'s body; instructing the subject to modify their cognitive state by activating the portable TES applicator, wherein the portable TES applicator is configured to deliver a pulsed, asymmetric, biphasic transdermal electrical stimulation between the first and second electrodes, the biphasic transdermal electric stimulation having a duty cycle of greater than 10 percent, a frequency of 750 Hz or greater, an intensity of 3 mA or greater than 5 mA, and wherein the stimulation is not charge balanced.
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21. A method of enhancing attention, alertness, or mental focus, the method comprising:
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placing a first electrode of a wearable transdermal electrical stimulation (TES) applicator on a subject'"'"'s skin on a temple region on a first side of the subject'"'"'s body; placing a second electrode on the subject'"'"'s skin in the mastoid region of the first side of the subject'"'"'s body; activating the wearable TES applicator to deliver a pulsed, asymmetric, biphasic transdermal electrical stimulation having a duty cycle of greater than 10 percent, a frequency of 750 Hz or greater, and an intensity of greater than 5 mA; and enhancing attention, alertness or mental focus by applying the biphasic transdermal electrical stimulation between the first and second electrodes for 10 seconds or longer. - View Dependent Claims (22, 23, 24, 25)
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26. A method of enhancing a calm or relaxed mental state, the method comprising:
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placing a first electrode of a wearable transdermal electrical stimulation (TES) applicator on a subject'"'"'s skin on a temple region on a first side of the subject'"'"'s body; placing a second electrode on the back of the subject'"'"'s neck above the vertebra prominens; activating the wearable TES applicator to deliver a pulsed, asymmetric, biphasic transdermal electrical stimulation having a duty cycle of greater than 10 percent, a frequency of 750 Hz or greater, and an intensity of greater than 5 mA; and enhancing a calm or relaxed mental state by applying the biphasic transdermal electrical stimulation between the first and second electrodes for 10 seconds or longer. - View Dependent Claims (27, 28, 29, 30)
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Specification