Devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications

  • US 9,113,836 B2
  • Filed: 03/02/2010
  • Issued: 08/25/2015
  • Est. Priority Date: 03/02/2009
  • Status: Active Grant
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First Claim
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1. A device for analysis of an extractable medium from the skin and/or from beneath the skin of a subject, the device comprising:

  • a support structure constructed and arranged to be positioned proximate the skin of the subject;

    a plurality of microneedles associated with the support structure for accessing the extractable medium from and/or through the skin of the subject at an access site;

    a pressure regulator supported by the support structure, able to create a pressure differential across the skin at at least a portion of the access site, wherein the pressure regulator comprises a vacuum chamber having an internal pressure less than atmospheric pressure before the device is applied to the skin of the subject;

    a sensor supported by the support structure, for determining at least one condition of the extractable medium from the subject;

    a signal generator supported by the support structure, for generating a signal relating to the condition of the medium determined by the sensor,wherein the support structure is constructed and arranged to move the plurality of microneedles into contact with the skin, and to withdrawal the plurality of microneedles from the skin after contact with the skin.

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