Inhibitors of bruton's tyrosine kinase
1. A compound of Formula (A5) having the structure:
Described herein are irreversible kinase inhibitor compounds exemplified by the following structure Formula (A2):
methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of a B cell proliferative disorder or a mast cell proliferative disorder.
- 1. A compound of Formula (A5) having the structure: