Systems and methods for replacing signal artifacts in a glucose sensor data stream

  • US 9,149,219 B2
  • Filed: 02/09/2011
  • Issued: 10/06/2015
  • Est. Priority Date: 08/22/2003
  • Status: Active Grant
First Claim
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1. A computer-implemented method for administering a medicament therapy to a host, comprising:

  • monitoring a data stream from a glucose sensor, the data stream indicative of a glucose concentration of a host;

    calibrating the data stream;

    detecting transient non-glucose related signal artifacts and evaluating a severity thereof;

    replacing with an electronic device at least some of the signal artifacts with one or more physiologically feasible estimated glucose values in response to the evaluated severity, wherein replacing at least some of the signal artifacts comprises estimating a glucose concentration value, wherein estimating utilizes physiological information along with the data stream in order determine the one or more physiologically feasible estimated glucose values; and

    controlling administration of a medicament to the host, using a medicament delivery device, based on the one or more physiologically feasible estimated glucose values.

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