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Polymer membranes for continuous analyte sensors

  • US 9,173,606 B2
  • Filed: 01/30/2014
  • Issued: 11/03/2015
  • Est. Priority Date: 03/28/2008
  • Status: Active Grant
First Claim
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1. A system for measurement of an analyte concentration, the system comprising:

  • an implantable sensor comprising a sensing region configured to continuously produce in vivo sensor data indicative of an analyte concentration in a host, wherein the sensor further comprises a membrane located over the sensing region, wherein the membrane comprises a layer configured to reduce a flux of the analyte therethrough, wherein the layer comprises a material that is a polymer produced by a reaction of an isocyanate;

    a processor configured to process sensor data; and

    a user interface configured to display information corresponding to continuous sensor data;

    wherein the sensor is configured to provide, at analyte concentrations of from 40 mg/dL to 400 mg/dL, a level of accuracy corresponding to a mean absolute relative difference of less than 10% over a sensor session length of from 3 to 7 days, wherein one or more reference measurements used to calculate the mean absolute relative difference are determined by analysis of blood.

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