Sleep apnea treatment

• US 9,186,504 B2
• Filed: 12/03/2014
• Issued: 11/17/2015
• Est. Priority Date: 11/15/2010
• Status: Active Grant

• Current Assignee: BlueWind Medical Ltd.
• Original Assignee: Rainbow Medical Ltd.
• Inventors: Gross, Yossi
• Primary Examiner(s): Kahelin, Michael
• Assistant Examiner(s): FAIRCHILD, MALLIKA DIPAYAN
• Application Number:
  US14/559,907
• Publication Number:
  US 20150148861A1
• Time in Patent Office: 349 Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/3601 of respiratory organs
• CPC Class Codes: A61N 1/37223 Circuits for electromagnetic coupling
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

Apparatus and methods are described, including apparatus for treating a subject for obstructive sleep apnea (OSA). The apparatus includes an implant, an imaging device, and a control unit. In response to a set of training images received from the imaging device, the control unit learns an association between a position of a head of the subject and OSA of the subject. In response to the association, the control unit establishes, for an OSA-related parameter, at least two distinct thresholds corresponding to respective different head positions. Subsequently, at a second time, the control unit selects a threshold that corresponds to the position of the subject'"'"'s head, and if the value of the OSA-related parameter passes the selected threshold, treats the subject for OSA by driving the implant to apply current to an anatomical site of the subject. Other applications are also described.

Claims

1. Apparatus for treating a subject for obstructive sleep apnea (OSA), the apparatus comprising:

an implant, comprising;

a wireless receiver;

two or more electrodes; and

circuitry coupled to the electrodes;

an imaging device configured to generate images of the subject while the subject sleeps;

at least one antenna; and

a control unit configured to;

at a first time, in response to a set of training images received from the imaging device;

learn an association between a position of a head of the subject and OSA of the subject, and

in response to the association, establish, for an OSA-related parameter, at least two distinct thresholds corresponding to respective different head positions, and

at a second time following the first time, in response to a second-time position of the subject'"'"'s head exhibited in a second-time image received from the imaging device;

select, from the established thresholds, a threshold that corresponds to the second-time position of the subject'"'"'s head, and

when a second-time value of the OSA-related parameter passes the selected threshold, treat the subject for OSA by driving the antenna to transmit a signal to the wireless receiver, the wireless receiver being configured to receive the signal, and the circuitry being configured to drive the electrodes to apply current to an anatomical site of the subject in response to the received signal.

2. The apparatus according to claim 1, wherein the implant is configured to be implanted sublingually.

3. The apparatus according to claim 2, wherein the two or more electrodes are configured to be coupled to a sublingual muscle of the subject.

4. The apparatus according to claim 1, further comprising a breathing sensor configured to sense the second-time value of the OSA-related parameter by sensing activity associated with breathing of the subject.

5. The apparatus according to claim 4, wherein the breathing sensor is configured to sense activity associated with breathing of the subject by sensing a phenomenon selected from the group consisting of:

airway pressure, snoring sounds, snoring motions, mechanical motion, and electrical activity.

6. A method for treating a subject for obstructive sleep apnea (OSA), the method comprising:

using an imaging device, generating a set of training images of the subject while the subject sleeps;

using a control unit;

in response to the set of training images, learning an association between a position of a head of the subject and OSA of the subject; and

in response to the association, establishing, for an OSA-related parameter, at least two distinct thresholds corresponding to respective different head positions;

using the imaging device, generating a second-time image of the subject while the subject sleeps; and

using the control unit, in response to a second-time position of the subject'"'"'s head exhibited in the second-time image;

selecting, from the established thresholds, a threshold that corresponds to the second-time position of the subject'"'"'s head, and

when a second-time value of the OSA-related parameter passes the selected threshold, treating the subject for OSA by driving an implant to apply current to an anatomical site of the subject.

7. The method according to claim 6,

wherein the method is for use with at least one antenna,

wherein the implant includes a wireless receiver, two or more electrodes, and circuitry coupled to the electrodes, and

wherein treating the subject comprises:

using the control unit to drive the antenna to transmit a signal to the wireless receiver; and

using the circuitry, driving the electrodes to apply current to the anatomical site of the subject, in response to the signal.

8. The method according to claim 7, further comprising implanting the implant in the subject.

9. The method according to claim 8, wherein implanting the implant in the subject comprises sublingually implanting the implant.

10. The method according to claim 6, further comprising using a breathing sensor to sense the second-time value of the OSA-related parameter by sensing activity associated with breathing of the subject.

11. The method according to claim 10, wherein sensing activity associated with breathing of the subject comprises sensing activity associated with breathing of the subject by sensing a phenomenon selected from the group consisting of:

airway pressure, snoring sounds, snoring motions, mechanical motion, and electrical activity.

12. Apparatus for treating a subject for obstructive sleep apnea (OSA), the apparatus comprising:

an implant, comprising;

a wireless receiver;

two or more electrodes; and

circuitry coupled to the electrodes;

an imaging device configured to generate images of the subject while the subject sleeps;

at least one antenna; and

a control unit configured to;

at a first time, in response to a set of training images received from the imaging device, learn an association between a position of a head of the subject and OSA of the subject, and

at a second time following the first time, in response to (a) a second-time position of the subject'"'"'s head exhibited in a second-time image received from the imaging device, and (b) the learned association, treat the subject for OSA by driving the antenna to transmit a signal to the wireless receiver, the wireless receiver being configured to receive the signal, and the circuitry being configured to drive the electrodes to apply current to an anatomical site of the subject in response to the received signal.