Portable drug mixing and delivery system and method

• US 9,199,037 B2
• Filed: 03/18/2014
• Issued: 12/01/2015
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: WindGap Medical Inc.
• Original Assignee: WindGap Medical Inc.
• Inventors: Buchine, Brent Alan, Stepanian, Christopher John, Standley, Adam
• Primary Examiner(s): HAYMAN, IMANI N
• Application Number:
  US14/218,355
• Publication Number:
  US 20140276385A1
• Time in Patent Office: 623 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/202 cocking means, e.g. to bias the main drive spring of an injector
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

A portable auto-injector configured to store various wet and dry medicament components separately. Wherein prior to injection the various medicaments within the portable auto-injector are mixed through a multi-stage process in one or more chambers within the portable auto-injector. The various chambers being connected by corresponding fluidic channels.

Claims

1. A drug mixing system comprising:

a housing comprising a first and second chamber, wherein the first chamber is configured to store a wet component;

a movable body disposed between the first and second chambers, the movable body further comprising;

a fluidic channel being disposed therein and configured to allow fluid communication between the first and second chamber; and

a dry medicament being contained within the fluidic channel; and

an actuation device configured to cause a portion of the movable body to enter a portion of the first and second chambers, the entrance of the movable body into a portion of the first and second chambers creating fluid communication between the fluidic channel and the first and second chambers, thereby forcing a portion of the wet component from the first chamber through the fluidic channel into the second chamber.

2. The drug mixing system of claim 1, wherein the second chamber is configured to store a second wet component.

3. The drug mixing system of claim 2, wherein the first and second wet components are comprised of either an acid or base.

4. The drug mixing system of claim 3, wherein when the first and second wet components combine to help dissolve the dry medicament.

5. The drug mixing system of claim 1, wherein the fluid communication caused by the actuation device results in the wet component in the first chamber and the dry medicament component in contact with the fluidic channel to combine.

6. The drug mixing system of claim 1, further comprising a needle assembly in fluid communication with the second chamber.

7. The drug mixing system of claim 5, wherein a second actuation device causes combined wet and dry medicament components to pass from the second chamber and through the needle assembly.

8. The drug mixing system of claim 1, further comprising a telescoping component attached to the housing, and whereby an extension of the telescoping component causes the actuation device to actuate.

9. The drug mixing system of claim 1, further comprising an unfolding component attached to the housing, and whereby an unfolding of the unfolding component causes the actuation device to actuate.

10. The fluidic channel of claim 1, further comprising a plurality of grooves formed in a portion of a sidewall of the fluidic channel.

11. A drug mixing and delivery system comprising:

a housing comprising a first and second chamber, wherein the first chamber is configured to store a wet component;

a movable body disposed between the first and second chambers, the movable body further comprising;

a fluidic channel being disposed therein and configured to allow fluidic communication between the first and second chambers; and

a dry medicament provided within the fluidic channel;

a first actuation device configured to cause a portion of the movable body to enter a portion of the first and second chambers, creating fluid communication between the fluidic channel and the first and second chambers, thereby forcing a portion of the wet component from the first chamber through the fluidic channel into the second chamber;

a delivery assembly at least partially disposed in the housing; and

a second actuation device and whereupon activation causes the movable body to enter into a portion of the second chamber, creating a fluid communication between the second chamber and the delivery assembly and forcing the combined wet component and dry medicament through the delivery assembly.

12. The drug mixing and delivery system of claim 11, further comprising an extension component incorporated into the housing and configured to increase the effective length of the housing.

13. The drug mixing and delivery system of claim 12, wherein the extension component is a telescoping component.

14. The drug mixing and delivery system of claim 12, wherein the extension component is an unfolding component.

15. The drug mixing and delivery system of claim 12, wherein an extension extending from the extension component causes the first actuation device to actuate.

16. The drug mixing and delivery system of claim 11, further comprising a safety configured to enable the second actuation device to be actuated when the safety is placed in a ready position.

17. The drug mixing and delivery system of claim 11, wherein the first actuation device is comprised of a pre-loaded spring.

18. A drug mixing and delivery system comprising:

a housing comprising a first and second chamber, wherein the first chamber is configured to store a wet component;

a movable body disposed between the first and second chambers, the movable body further comprising;

a fluidic channel being disposed therein and configured to allow fluidic communication between the first and second chambers;

a dry medicament provided within the fluidic channel; and

wherein the fluidic channel has one or more features contained therein forming a mixing assembly;

a first actuation device configured to cause a portion of the movable body to enter a portion of the first and second chambers, creating fluid communication between the fluidic channel and the first and second chambers, thereby forcing a portion of the wet component from the first chamber through the fluidic channel into the second chamber;

a delivery assembly at least partially disposed in the housing; and

a second actuation device and whereupon activation causes the movable body to enter into a portion of the second chamber, creating a fluid communication between the second chamber and the delivery assembly and forcing the combined wet component and dry medicament through the delivery assembly.

19. The drug mixing and delivery system of claim 18, wherein the one or more features include one or more features selected from a group consisting of:

a plurality of grooves;

bends in the fluidic channel; and

one or more obstructions along the length of the fluidic channel.