Sulfoalkyl ether cyclodextrin compositions

  • US 9,200,088 B2
  • Filed: 03/07/2013
  • Issued: 12/01/2015
  • Est. Priority Date: 04/28/2008
  • Status: Active Grant
First Claim
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1. A sulfoalkyl ether cyclodextrin (SAE-CD) composition that can be readily mixed with an active agent, comprising a sulfoalkyl ether cyclodextrin having an average degree of substitution of 4.5 to 7.5 and less than 200 ppm of a phosphate, wherein the SAE-CD composition has an absorption of less than 0.5 A.U. due to a UV-active impurity as determined by UV/vis spectrophotometry at a wavelength of 245 nm to 270 nm for an aqueous solution containing 300 mg of the SAE-CD composition per mL of solution in a cell having a 1 cm path length.

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