Delivery device and method
First Claim
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1. A delivery device for delivering substance to a mucosal surface within the oral cavity of a subject, the device comprising:
- a mouthpiece unit to be gripped in the mouth of a subject, wherein the mouthpiece unit is configured such that, on exhalation or attempted exhalation by the subject into the mouthpiece unit, a pressure is developed in the oral cavity which closes the oropharyngeal velum of the subject;
an oral outlet unit including at least one substance outlet from which substance is delivered to a mucosal surface within the oral cavity of the subject when the subject exhales or attempts to exhale through the mouthpiece unit; and
a breath-actuated delivery unit including a substance supply unit which is actuatable to deliver substance from the at least one substance outlet.
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Abstract
A delivery device for and method of delivering substance, in particular a vaccine, to a mucosal surface within the oral cavity of a subject, the device comprising: a mouthpiece unit to be gripped in the mouth of a subject, wherein the mouthpiece unit is configured such that, on exhalation or attempted exhalation by the subject, a pressure is developed in the oral cavity which is such as to close the oropharyngeal velum of the subject; and an oral outlet unit including at least one outlet from which substance is in use delivered to a mucosal surface within the oral cavity of the subject.
37 Citations
19 Claims
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1. A delivery device for delivering substance to a mucosal surface within the oral cavity of a subject, the device comprising:
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a mouthpiece unit to be gripped in the mouth of a subject, wherein the mouthpiece unit is configured such that, on exhalation or attempted exhalation by the subject into the mouthpiece unit, a pressure is developed in the oral cavity which closes the oropharyngeal velum of the subject; an oral outlet unit including at least one substance outlet from which substance is delivered to a mucosal surface within the oral cavity of the subject when the subject exhales or attempts to exhale through the mouthpiece unit; and a breath-actuated delivery unit including a substance supply unit which is actuatable to deliver substance from the at least one substance outlet. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification