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Systems, methods and devices for achieving glycemic balance

  • US 9,220,456 B2
  • Filed: 06/24/2011
  • Issued: 12/29/2015
  • Est. Priority Date: 04/04/2008
  • Status: Active Grant
First Claim
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1. A method for treating a patient'"'"'s diabetes by providing treatment guidance, the method comprising:

  • storing one or more components of the patient'"'"'s insulin dosage regimen;

    obtaining data corresponding to the patient'"'"'s blood glucose-level measurements determined at a plurality of times;

    initiating a timer to monitor the predetermined time period;

    incrementing the timer based on at least one of the passage of a predetermined increment of time and the receipt of at least one of the plurality of blood glucose-level measurements;

    tagging the blood glucose-level measurements with an identifier reflective of when or why the reading was obtained;

    determining, after obtaining one of the plurality of blood glucose-level measurements but before obtaining a subsequent blood glucose-level measurement, the patient'"'"'s current glycemic state relative to a desired balance point; and

    determining from at least one of a plurality of the data corresponding to the patient'"'"'s blood glucose-level measurements whether and by how much to vary at least one of the one or more components in the patient'"'"'s present insulin dosage regimen to get closer to the patient'"'"'s desired glycemic balance point;

    reducing at least one of the one or more components in the patient'"'"'s insulin dosage regimen in response to the determination that the most recently obtained blood glucose-level measurement represents a severe hypoglycemic event;

    reducing at least one of the one or more components in the patient'"'"'s insulin dosage regimen in response to a determination that the most recently obtained blood glucose-level measurement results in an excessive number of hypoglycemic events during the predetermined time period;

    wherein the timer is reinitiated after the determination that there have been an excessive number of hypoglycemic events over the predetermined amount of time; and

    determining at the end of the predetermined time period, from a plurality of the data corresponding to the patient'"'"'s blood glucose-level measurements whether and by how much to vary at least one of the one or more components in the patient'"'"'s present insulin dosage regimen in order to maintain the patient'"'"'s blood glucose-level measurements within a predefined range;

    wherein the timer is reinitiated after the determination of whether and by how much to vary at least one of the one or more components in the patient'"'"'s present insulin dosage regimen;

    wherein the desired glycemic balance point is the patient'"'"'s lowest blood glucose-level within a predetermined range achievable before increasing the frequency of hypoglycemic events above a predetermined threshold.

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