Method and device for drug delivery

  • US 9,220,837 B2
  • Filed: 06/21/2007
  • Issued: 12/29/2015
  • Est. Priority Date: 03/19/2007
  • Status: Active Grant
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First Claim
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1. A system for delivery of a therapeutic first substance from a reservoir of a drug delivery pump to a body of a patient, comprising;

  • a drug delivery pump comprising a reservoir to contain the therapeutic first substance;

    an infusion catheter configured to be inserted subcutaneously into a tissue of the patient at an insertion site, wherein a volume of tissue surrounding the insertion site comprises an infused region;

    a catheter securing element configured to be adhered to skin of the patient and further configured to secure the infusion catheter within the tissue of the patient;

    a tubing configured to transport the therapeutic first substance between the reservoir of the drug delivery pump and the infusion catheter; and

    a treatment element comprising a heater included with the catheter securing element and affixed thereto and configured to apply a treatment to a vicinity of the infused region to modify a pharmacodynamics profile of the therapeutic first substance,whereinthe drug delivery pump is configured to infuse the therapeutic first substance into the infusion catheter for delivery to the infused region, andthe heater is configured to heat the infused region without heating the reservoir and without heating any of the therapeutic first substance and the tubing above a predetermined limiting temperature above which degrades the therapeutic first substance prior to infusion of the therapeutic first substance into the infused region or prior to the therapeutic first substance being infused into the infusion catheter.

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