Methods of treating acne

  • US 9,241,946 B2
  • Filed: 06/29/2015
  • Issued: 01/26/2016
  • Est. Priority Date: 04/05/2001
  • Status: Active Grant
First Claim
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1. A method for treating acne in a human in need thereof, the method comprisingadministering orally to said human doxycycline, or a pharmaceutically acceptable salt thereof,in an amount that(i) is effective to treat acne;

  • (ii) is 10-80% of a 50 mg dose of doxycycline per day; and

    (iii) results in no reduction of skin microflora during a six-month treatment, without administering a bisphosphonate compound,wherein said doxycycline, or a pharmaceutically acceptable salt thereof, is administered in an amount which provides a serum concentration in the range of about 0.1 to about 0.8 μ


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