antigens and compositions

  • US 9,266,929 B2
  • Filed: 08/01/2014
  • Issued: 02/23/2016
  • Est. Priority Date: 05/01/1998
  • Status: Expired due to Fees
First Claim
Patent Images

1. A method of preparing an immunogenic composition comprising:

  • (a) expressing in E. coli a polypeptide comprising a fragment of the amino acid sequence of SEQ ID NO;

    2536, wherein the fragment comprises 16 or more consecutive amino acids from the amino acid sequence, wherein the polypeptide is immunogenic;

    (b) purifying the polypeptide;

    (c) preparing the immunogenic composition by combining the purified polypeptide with an aluminum salt adjuvant.

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