Method and apparatus for evaluating values representing a mass or a concentration of a substance present within the body of a patient
First Claim
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1. A method for evaluating a value representing a mass or a concentration or a volume of a substance contained in a tissue or a bodily fluid of a patient, comprising the steps of:
- determining, by a processor, a relation between one or more calculated or measured value(s) reflecting;
(a) the mass or the concentration or the volume of the substance contained in the tissue or the bodily fluid of the patient or an approximation thereof, and(b) a distribution space of the patient or an approximation thereof, the distribution space being a body fluid, a body tissue, a body weight, a total body mass, a combination of the body fluid and the body tissue, or a space of the patient, wherein the distribution space is based on calculated or measured values reflecting a relative overhydration (relOH) of the patient or an absolute overhydration (OH) of the patient;
assessing, by the processor, whether the relation fulfils at least one criterion; and
determining or adjusting a dosage of a medicament to be administered to the patient based on the assessing whether the relation fulfills the at least one criterion,wherein the dosage of the medicament is administered to the patient for improving an anemia state of the patient.
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Abstract
The present invention relates to a method for evaluating a value representing the mass or the concentration of a substance comprised by a tissue or a bodily fluid of a patient, the method including the steps of a) determining a relation between one or more calculated or measured value(s) reflecting the mass or the concentration and a distribution space of the patient or an approximation thereof, and b) assessing whether the relation fulfills a criterion. The present invention further relates to systems and computer programs for performing this method.
8 Citations
21 Claims
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1. A method for evaluating a value representing a mass or a concentration or a volume of a substance contained in a tissue or a bodily fluid of a patient, comprising the steps of:
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determining, by a processor, a relation between one or more calculated or measured value(s) reflecting; (a) the mass or the concentration or the volume of the substance contained in the tissue or the bodily fluid of the patient or an approximation thereof, and (b) a distribution space of the patient or an approximation thereof, the distribution space being a body fluid, a body tissue, a body weight, a total body mass, a combination of the body fluid and the body tissue, or a space of the patient, wherein the distribution space is based on calculated or measured values reflecting a relative overhydration (relOH) of the patient or an absolute overhydration (OH) of the patient; assessing, by the processor, whether the relation fulfils at least one criterion; and determining or adjusting a dosage of a medicament to be administered to the patient based on the assessing whether the relation fulfills the at least one criterion, wherein the dosage of the medicament is administered to the patient for improving an anemia state of the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A system for evaluating a value representing a mass or a concentration or a volume of a substance contained in a tissue or a bodily fluid of a patient, comprising a controller configured to:
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determine a relation between one or more calculated or measured value(s) reflecting; (a) the mass or the concentration or the volume of the substance contained in the tissue or the bodily fluid of the patient or an approximation thereof, and (b) a distribution space of the patient or an approximation thereof, the distribution space being a body fluid, a body tissue, a body weight, a total body mass, a combination of the body fluid and the body tissue, or a space of the patient, wherein the distribution space is based on calculated or measured values reflecting a relative overhydration (relOH) of the patient or an absolute overhydration (OH) of the patient; assess whether the relation fulfils at least one criterion; and determine or adjust a dosage of a medicament to be administered to the patient based on the assessing whether the relation fulfills the at least one criterion, wherein the dosage of the medicament is administered to the patient for improving an anemia state of the patient. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
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21. A non-transitory computer-readable medium with an executable program stored thereon, wherein the program instructs a programmable computer system to perform the following steps for evaluating a value representing a mass or a concentration or a volume of a substance contained in a tissue or a bodily fluid of a patient:
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determining a relation between one or more calculated or measured value(s) reflecting; (a) the mass or the concentration or the volume of the substance contained in the tissue or the bodily fluid of the patient or an approximation thereof, and (b) a distribution space of the patient or an approximation thereof, the distribution space being a body fluid, a body tissue, a body weight, a total body mass, a combination of the body fluid and the body tissue, or a space of the patient, wherein the distribution space is based on calculated or measured values reflecting a relative overhydration (relOH) of the patient or an absolute overhydration (OH) of the patient; assessing whether the relation fulfils at least one criterion; and determining or adjust a dosage of a medicament to be administered to the patient based on the assessing whether the relation fulfills the at least one criterion, wherein the dosage of the medicament is administered to the patient for improving an anemia state of the patient.
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Specification