Contact lens with a hydrophilic layer

• US 9,310,627 B2
• Filed: 03/17/2015
• Issued: 04/12/2016
• Est. Priority Date: 11/15/2013
• Status: Active Grant

• Current Assignee: Tangible Science, Llc
• Original Assignee: Ocular Dynamics, LLC
• Inventors: Havenstrite, Karen L., McCray, Victor Wayne, Felkins, Brandon McNary, Cook, Paul A.
• Primary Examiner(s): Sugarman, Scott J
• Application Number:
  US14/660,728
• Publication Number:
  US 20150234204A1
• Time in Patent Office: 392 Days
• Field of Search: 351/159.02
• US Class Current: 1/1
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/02 Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: B29D 11/00 Producing optical elements, e.g. lenses or prisms grinding or polishing of optical elements B24B; constructional form of optical elements G02B; optical parts of spectacles G02C7/00
• CPC Class Codes: B29D 11/00788 Producing optical films
• CPC Class Codes: C08L 101/14 the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
• CPC Class Codes: C08L 33/10 Homopolymers or copolymers of methacrylic acid esters
• CPC Class Codes: C08L 33/26 Homopolymers or copolymers of acrylamide or methacrylamide
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: C09D 171/00 Coating compositions based on polyethers obtained by reactions forming an ether link in the main chain based on polyacetals C09D159/00; based on epoxy resins C09D163/00; based on polythioether-ethers C09D181/02; based on polyethersulfones C09D181/06; Coating compositions based on derivatives of such polymers
• CPC Class Codes: G02B 1/043 Contact lenses
• CPC Class Codes: G02C 2202/16 Laminated or compound lenses
• CPC Class Codes: G02C 7/04 Contact lenses for the eyes disinfection or sterilisation of contact lenses A61L12/00
• CPC Class Codes: G02C 7/049 Contact lenses having special fitting or structural features achieved by special materials or material structures

Abstract

Embodiments of the technology relate to a contact lens having a core that is coated by a hydrogel layer, and to methods of making such a lens. The coated lens can include a rigid gas permeable contact lens. The coated lens can also include a hybrid silicone and rigid gas permeable contact lens. In one aspect, embodiments provide for a coated contact lens comprising a lens core with a water equilibrium constant of less than about 2% comprising an outer surface; and a hydrogel layer covalently attached to at least a portion of the outer surface, the hydrogel layer adapted to contact an ophthalmic surface, wherein the hydrogel layer comprises a hydrophilic polymer population of one or more species.

Claims

1. A multi-layer contact lens comprising a lens core layer covered by an outer hydrophilic polymer layer, wherein the hydrophilic polymer layer is attached to the core layer by a covalent linkage, wherein the hydrophilic polymer layer comprises a first macromer subpopulation comprising polyethylene glycol (PEG) and a second macromer subpopulation comprising polyacrylamide, wherein the first macromer subpopulation and second macromer subpopulations are at least partially covalently cross-linked, wherein the hydrophilic polymer layer has a thickness of less than about 50 nm.

2. The lens of claim 1, wherein the core comprises a hydrogel.

3. The lens of claim 1, wherein the core comprises a silicone hydrogel.

4. The lens of claim 1, wherein the lens core layer comprises a rigid gas permeable lens material.

5. The lens of claim 1, wherein the first macromer subpopulation comprises a moiety at a first portion that forms a covalent attachment to the outer surface of the lens core layer;

and the second macromer subpopulation comprises a second moiety that forms a covalent bond to a second portion of the first macromer subpopulation.

6. The lens of claim 5, wherein the core comprises a hydrogel.

7. The lens of claim 5, wherein the core comprises a silicone hydrogel.

8. The lens of claim 5, wherein the lens core layer comprises a rigid gas permeable lens material.

9. The lens of claim 1 wherein the lens core layer comprises a bifunctional monomer or polymer covalently bound to the lens core layer and the outer hydrophilic polymer layer.

10. The lens of claim 9, wherein the lens core layer comprises a hydrogel.

11. The lens of claim 9, wherein the lens core layer comprises a silicone hydrogel.

12. The lens of claim 9, wherein the lens core layer comprises a rigid gas permeable lens material.