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Method and apparatus for fractional flow reserve measurements

  • US 9,314,584 B1
  • Filed: 06/27/2012
  • Issued: 04/19/2016
  • Est. Priority Date: 06/27/2011
  • Status: Active Grant
First Claim
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1. A method of determining fractional flow reserve (FFR) in a blood vessel having stenosis comprising:

  • placing a pressure sensor proximal of the stenosis;

    injecting fluid with a fluid delivery system into the blood vessel proximal of the stenosis using a power fluid injector to identify a flow rate through the blood vessel;

    measuring pressure in the blood vessel proximal of the stenosis during injection of the fluid with the fluid delivery system;

    measuring pressure drop across the stenosis with the fluid delivery system based on the flow rate during injecting of the fluid with the power fluid injector; and

    calculating FFR from the measured pressure drop with the fluid delivery system,wherein injecting fluid into the blood vessel is reduced or discontinued when retrograde flow is present in the blood vessel.

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