Analyte sensor with time lag compensation

• US 9,320,468 B2
• Filed: 06/21/2013
• Issued: 04/26/2016
• Est. Priority Date: 01/31/2008
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Hayter, Gary Alan, Doniger, Kenneth J., Budiman, Erwin Satrya
• Primary Examiner(s): JANG, CHRISTIAN YONGKYUN
• Application Number:
  US13/924,528
• Publication Number:
  US 20130281807A1
• Time in Patent Office: 1,040 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence

Abstract

Methods and devices and systems for determining an analyte value are disclosed.

Claims

1. A computer implemented method, comprising:

determining a rate of change of a monitored analyte level;

determining a lag time constant associated with calibrated analyte data using a reference measurement, the monitored analyte level, and the rate of change of the monitored analyte level;

performing lag correction of the calibrated analyte data based on the determined time lag constant; and

controlling administration of therapy based on performing the lag correction of the calibrated analyte data.

2. The method of claim 1, including outputting the lag corrected calibrated analyte data.

3. The method of claim 1, wherein the reference measurement includes a blood glucose measurement.

4. The method of claim 1, wherein the reference measurement is obtained within a predetermined time period relative to the monitored analyte level.

5. The method of claim 1, wherein determining the rate of change includes determining a rate of increase or a rate of decrease of the monitored analyte level for a predefined time period.

6. The method of claim 1, wherein the monitored analyte level is obtained using an analyte sensor.

7. The method of claim 6, wherein the analyte sensor includes one of a lactate sensor or a glucose sensor.

8. The method of claim 1, wherein determining the lag time constant includes pairing the reference measurement with an analyte sensor data corresponding to the monitored analyte level obtained when the reference measurement is obtained.

9. The method of claim 1, wherein determining the lag time constant includes pairing the reference measurement with an analyte sensor value based on a plurality of analyte sensor data corresponding to the monitored analyte level obtained before and after the reference measurement is obtained.

10. The method of claim 1, wherein the lag time constant is determined using multi-dimensional least squares technique.

11. The method of claim 1, wherein controlling administration of therapy includes modifying a medication delivery rate.

12. The method of claim 11, wherein the medication delivery rate includes one or more of a basal delivery profile or a bolus dose delivery profile.

13. The method of claim 11, wherein the medication delivery rate includes insulin delivery rate.