Methods and compositions for the treatment of symptoms of Williams Syndrome
First Claim
1. A method for treating Williams Syndrome in a patient diagnosed with Williams Syndrome comprising administering to the patient a therapeutically effective amount of a pharmaceutical composition comprising digestive enzymes, wherein said digestive enzymes comprise a protease, a lipase and an amylase, and wherein the patient exhibits abdominal pain.
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Abstract
A therapeutic composition for the treatment of the symptoms of Williams Syndrome and the method for preparing the therapeutic agents is disclosed. The therapeutic composition is a stable pharmaceutical composition comprising one or more digestive and/or pancreatic enzymes. The therapeutic composition may be manufactured by a variety of encapsulation technologies. Delivery of the therapeutic composition may be made orally, through injection, by adherence of a medicated patch or other method. Further, a method of using fecal chymotrypsin level as a biomarker for the presence of Williams Syndrome, or the likelihood of an individual to develop Williams Syndrome is disclosed.
253 Citations
18 Claims
- 1. A method for treating Williams Syndrome in a patient diagnosed with Williams Syndrome comprising administering to the patient a therapeutically effective amount of a pharmaceutical composition comprising digestive enzymes, wherein said digestive enzymes comprise a protease, a lipase and an amylase, and wherein the patient exhibits abdominal pain.
Specification