Sensor head for use with implantable devices

  • US 9,328,371 B2
  • Filed: 07/16/2013
  • Issued: 05/03/2016
  • Est. Priority Date: 07/27/2001
  • Status: Active Grant
First Claim
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1. An implantable continuous glucose sensor system configured for implantation in a host, the system comprising:

  • an electrode comprising an electroactive surface, wherein the electrode is configured for implantation and is configured to generate in vivo a signal indicative of glucose concentration in a host;

    a membrane comprising;

    a first domain configured to reduce a flux of glucose therethrough;

    a second domain comprising an enzyme configured to react with glucose to produce a measured species, wherein the second domain is located less distant to the electroactive surface than the first domain; and

    a third domain comprising an architecture that permits access to the electroactive surface only for species that have a molecular weight less than or about equal to a molecular weight of the measured species, wherein the third domain is located less distant to the electroactive surface than the second domain; and

    sensor electronics operably connected to the electrode and configured to measure the signal from the electrode.

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