Devices and methods for controlling expandable prostheses during deployment

• US 9,339,404 B2
• Filed: 07/15/2013
• Issued: 05/17/2016
• Est. Priority Date: 03/22/2007
• Status: Active Grant

• Current Assignee: JW Medical Systems Ltd
• Original Assignee: JW Medical Systems Ltd
• Inventors: Snow, David W., Demarais, Denise, Lin, Stuart
• Primary Examiner(s): Nguyen, Tuan V
• Assistant Examiner(s): EVERAGE, KEVIN D
• Application Number:
  US13/942,557
• Publication Number:
  US 20140018899A1
• Time in Patent Office: 1,037 Days
• Field of Search: 623/1.12, 623/1.16
• US Class Current: 1/1
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/9517 handle assemblies therefor
• CPC Class Codes: A61F 2/966 with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61F 2002/91541 Adjacent bands are arranged out of phase
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91591 Locking connectors, e.g. using male-female connections

Abstract

A catheter for delivering a prosthesis to a treatment site in a body lumen comprises an elongate flexible member and a sheath slidably disposed thereover. A plurality of self-expanding tubular prostheses are carried in axially spaced apart locations along the elongate member, within the sheath. The prostheses may be selectively interlocked with one another and are constrained by the sheath in a radially contracted configuration. The prostheses are separately releasable from the sheath when the sheath is retracted relative to the elongate member. The catheter also has a pusher member slidably disposed along the elongate member within the sheath. The pusher is adapted to move past the prostheses in a first direction without displacing the prostheses, while in a second direction the pusher engages a selected prosthesis so as to move the prosthesis with the pusher to interlock the selected prosthesis with a second prosthesis.

Claims

1. A catheter for delivering a prosthesis to a treatment site in a body lumen, the catheter comprising:

an elongate flexible member having a proximal end and a distal end;

a sheath slidably disposed over the elongate flexible member;

a plurality of self-expanding tubular prostheses carried in axially spaced-apart locations along the elongate flexible member and within the sheath, the plurality of self-expanding tubular prostheses adapted to be selectively interlocked with one another and constrained by the sheath in a radially contracted configuration, the prostheses being separately releasable from the sheath as the sheath is retracted relative to the elongate flexible member; and

a pusher member slidably disposed along the elongate flexible member within the sheath, the pusher member adapted to move past the prostheses in a first direction, while in a second direction the pusher member engages a selected prosthesis so as to move the prosthesis with the pusher member to interlock the selected prosthesis with a second prosthesis;

wherein the pusher member has an engagement member which is deflectable radially inward by contact with the prostheses when moved in the first direction.

2. The catheter of claim 1, further comprising a stopping element axially disposed along the elongate flexible member, the stopping element adapted to prevent the plurality of self-expanding tubular prostheses from being displaced past the distal end of the elongate flexible member when the pusher member is advanced distally.

3. The catheter of claim 1, further comprising a handle near the proximal end of the elongate flexible member and having a control mechanism adapted to move the sheath and pusher member.

4. The catheter of claim 1, wherein the pusher member is adapted to move past the prostheses in a first direction without displacement thereof.

5. The catheter of claim 1, wherein the pusher member is slidable through the prostheses and comprises a plurality of fingers projecting radially outwardly so as to slide past the prostheses in a first direction while in a second direction the fingers engage the selected prosthesis.

6. The catheter of claim 1, wherein the pusher member exerts substantially greater axial force against the plurality of self-expanding tubular prostheses when the pusher member is advanced distally than when the pusher member is retracted proximally.

7. The catheter of claim 1, further comprising a central lumen disposed within the elongate shaft and adapted to carry a guidewire.

8. The catheter of claim 1, wherein the plurality of self-expanding tubular prostheses carry a therapeutic agent adapted to be released therefrom.

9. The catheter of claim 8, wherein the therapeutic agent comprises an anti-restenosis agent.

10. The catheter of claim 1, wherein the plurality of self-expanding tubular prostheses have a length in the range of about 5 mm to about 50 mm.

11. The catheter of claim 1, wherein each of the plurality of tubular self-expanding prostheses has the same length.

12. The catheter of claim 1, wherein at least one of the plurality of self-expanding tubular prostheses has a different length than at least another of the prostheses.

13. The catheter of claim 1, wherein the prostheses are adapted to be interlocked with one another when pressed together.

14. The catheter of claim 13, wherein the prostheses are adapted to remain interlocked with one another after radially expanding.

15. The catheter of claim 1, wherein the prostheses comprise a plurality of substantially parallel columns of open cells, the columns spaced apart and formed from a zig-zag pattern of substantially axial struts joined together with a connector.

16. The catheter of claim 15, wherein a plurality of bridges join the columns of open cells together.

17. The catheter of claim 16, wherein the bridges are sigmoidally shaped.

18. The catheter of claim 15, wherein the connector comprises a U-shaped portion.

19. The catheter of claim 15, wherein the open cells in a first column are out of phase with the open cells in an adjacent column.

20. The catheter of claim 1, wherein the prostheses comprise an interlocking tab disposed on a first end of the prostheses and adapted to interlock with an adjacent prosthesis.

21. The catheter of claim 20, wherein the interlocking tab comprises an enlarged head region and a narrower neck region.

22. The catheter of claim 21, wherein the enlarged head region comprises an arcuate strut defining a narrow inlet portion and a wider receiving portion, the receiving portion adapted to receive and interlock with an interlocking tab on an adjacent prosthesis.

23. The catheter of claim 21, wherein the enlarged head is C-shaped.

24. The catheter of claim 21, wherein the enlarged head comprises a plurality of arcuate struts coupled to the prosthesis with a plurality of axial struts.

25. The catheter of claim 21, wherein the neck comprises a plurality of axial struts.

26. The catheter of claim 21, wherein the enlarged head comprises an arcuate strut forming a C-shape coupled to the prosthesis with an axial strut.

27. The catheter of claim 20, wherein the interlocking tab comprises a strut defining an aperture.

28. The catheter of claim 27, wherein the aperture is adapted to hold a radiopaque marker.

29. The catheter of claim 20, wherein the prostheses further comprise a female receiving tab on an opposite end of the prosthesis as the interlocking tab.

30. The catheter of claim 29, wherein the female tab comprises an arcuate strut defining a receptacle, the receptacle adapted to receive and interlock with an enlarged head of an adjacent prosthesis and wherein the arcuate strut is coupled to the prostheses with an axial strut.

31. The catheter of claim 30, wherein the receptacle is C-shaped.

32. The catheter of claim 29, wherein the female tab comprises an arcuate strut defining an aperture, the aperture adapted to hold a radiopaque marker.