Devices and methods for improving vision using laser photomiosis

• US 9,345,549 B2
• Filed: 02/22/2013
• Issued: 05/24/2016
• Est. Priority Date: 02/25/2012
• Status: Active Grant

• Current Assignee: Thrufocus Optics Incorporated
• Original Assignee: Thrufocus Optics Incorporated
• Inventors: Hickenbotham, Adam L.
• Primary Examiner(s): Jackson, Gary
• Assistant Examiner(s): Nganga, Boniface N
• Application Number:
  US13/775,071
• Publication Number:
  US 20130226161A1
• Time in Patent Office: 1,187 Days
• Field of Search: 606 4- 6
• US Class Current: 1/1
• CPC Class Codes: A61B 34/10 Computer-aided planning, simulation or modelling of surgical operations
• CPC Class Codes: A61F 2009/00876 Iris
• CPC Class Codes: A61F 2009/00897 Scanning mechanisms or algorithms
• CPC Class Codes: A61F 9/00745 using mechanical vibrations, e.g. ultrasonic
• CPC Class Codes: A61F 9/008 using laser
• CPC Class Codes: A61F 9/00829 Correction of higher orders
• CPC Class Codes: A61F 9/00838 Correction of presbyopia
• CPC Class Codes: F04C 2270/041 Controlled or regulated

Abstract

Systems and methods of improving vision using an ophthalmological laser system are provided. A predetermined pattern characterized by a plurality of positions along a plurality of spatially distributed iris tissues of an eye of a patient is obtained. A laser illumination light beam is aligned in accordance with one or more of the plurality of positions along the plurality of spatially distributed iris tissues. The laser illumination light beam is delivered in the predetermined pattern to the plurality of spatially distributed iris tissues of the patient. At least a subset of the spatially distributed iris tissues is cauterized by the delivery of the laser illumination light beam in the predetermined pattern, thereby resulting in a permanent decrease in diameter of the pupil of the eye.

Claims

1. An ophthalmological laser system comprising:

a laser, the radiation of which is focusable as a laser illumination light beam, wherein the laser is a pulse laser and the laser illumination light beam comprises a sequence of light pulses of average time duration between 10 milliseconds and 100 milliseconds;

at least one processor;

memory;

at least one program stored in the memory and executable by the at least one processor, the at least one program comprising instructions to;

obtain a predetermined pattern characterized by a plurality of positions along an iris dilator muscle tissue of an eye of a patient;

align said laser illumination light beam in accordance with one or more of the plurality of positions along the iris dilator muscle tissue;

deliver said laser illumination light beam in the predetermined pattern on a surface of the eye of the patient to target the iris dilator muscle tissue; and

cauterize at least a subset of the iris dilator muscle tissue to weaken dilator muscle, by the delivery of the laser illumination light beam in the predetermined pattern, thereby resulting in a permanent decrease in diameter of the pupil of the eye.

2. The ophthalmological system of claim 1, wherein the laser is a pulse laser and the laser illumination light beam comprises a sequence of a plurality of light pulses with an average repetition rate between two consecutive light pulses of the plurality of light pulses between 0.5 Hertz and 100 kiloHertz.

3. The ophthalmological system of claim 1, wherein said laser illumination light beam comprises laser light of wavelength between 500 nanometers and 1700 nanometers.

4. The ophthalmological system of claim 1, wherein the obtained predetermined pattern further defines one or more laser parameters and wherein the instructions to deliver said laser illumination light deliver the laser illumination light in accordance with the one or more laser parameters.

5. The ophthalmological system of claim 1, wherein the predetermined pattern includes one or more of:

a substantially radial pattern, a substantially circumferential pattern, a substantially circular spot pattern, or any combination thereof.

6. The ophthalmological system of claim 1, wherein:

the predetermined pattern is a substantially radial pattern;

the plurality of positions comprise N positions, each of the N positions oriented radially from the inner circumference of the iris proximal to the pupil to the outer circumference of the iris distal to the pupil; and

the N positions include a first position and a second position, the second position being adjacent to the first position and separated from the first position by a predefined angular separation.

7. The ophthalmological system of claim 6, wherein the predefined angular separation has a value between 10°

and 50° and

N is a positive integer of value between 4 and 36.

8. The ophthalmological system of claim 1, wherein:

the predetermined pattern is a substantially circumferential pattern;

the plurality of positions comprises N positions, each of the N positions occurring at a first predetermined distance along a radius of the iris measured from inner circumference of the iris;

the N positions together form the substantially circumferential pattern which is substantially concentric with and proximal to the inner circumference of the iris; and

the N positions include a first position and a second position adjacent to the first position, wherein a center of the first position is separated from a center of the second position by a predetermined separation along the circumferential pattern.

9. The ophthalmological system of claim 8, wherein the first predetermined distance has a value between 0.75 millimeters and 1.5 millimeters, the predetermined separation has a value between 50 micrometers and 300 micrometers, an average length of the first position has a value between 25 micrometers and 200 micrometers, and N is a positive integer of value between 4 and 20.

10. The ophthalmological system of claim 1, wherein:

the predetermined pattern is a substantially circumferential pattern;

the plurality of positions comprises N positions, each of the N positions occurring at a second predetermined distance along a radius of the iris measured from the outer circumference of the iris;

the N positions together form the substantially circumferential pattern which is substantially concentric with and proximal to the outer circumference of the iris; and

the N positions include a first position and a second position adjacent to the first position, wherein a center of the first position is separated from a center of the second position by a predetermined separation along the circumferential pattern.

11. The ophthalmological system of claim 10, wherein the second predetermined distance has a value between 0 and 1.5 millimeters, the predetermined separation has a value between 50 micrometers and 1 millimeter, an average length of the first position has a value between 25 micrometers and 500 micrometers, and N is a positive integer of value between 4 and 20.

12. The ophthalmological system of claim 1, wherein:

the predetermined pattern is a substantially circular spot pattern;

the plurality of positions comprises N positions, each of the N positions occurring at a predetermined distance along a radius of the iris measured from the inner circumference of the iris;

the N positions together form the substantially circular spot pattern which is substantially concentric with and proximal to the inner circumference of the iris; and

the N positions include a first spot position and a second spot position, the second spot position being adjacent to the first spot position, wherein a center of the first spot position is separated from a center of the second spot position by a predetermined separation along the substantially circular spot pattern.

13. The ophthalmological system of claim 12, wherein the predetermined distance has a value between 0.75 millimeters and 1.5 millimeters, the predetermined separation has a value less than 300 micrometers, an average radius of the first spot position has a value between 10 micrometers to 300 micrometers, and N is a positive integer of value between 4 and 20.

14. The ophthalmological system of claim 1, wherein:

the predetermined pattern is a substantially circumferential pattern; and

the plurality of positions comprises a (i) first set of M positions and (ii) a second set of P positions wherein;

each position of the first set of M positions occurs at a first predetermined distance along the radius of the iris measured from the inner circumference of the iris and the first set of M positions forms a first portion of the substantially circumferential pattern which is substantially concentric with and proximal to the inner circumference of the iris; and

each position of the second set of P positions occurs at a second predetermined distance along the radius of the iris measured from the outer circumference of the iris and the first set of P positions forms a second portion of the substantially circumferential pattern which is substantially concentric with and proximal to the outer circumference of the iris.

15. The ophthalmological system of claim 14, wherein:

the first set of M positions includes (i) a first position with a center located along a first radial vector measured from the center of the pupil toward the outer circumference of the iris and (ii) a second position, adjacent to the first position among the first set of M positions, located along a second radial vector measured from the center of the pupil toward the outer circumference of the iris; and

the second set of P positions includes a third position along the first radial vector and a fourth position adjacent to the third position along the second radial vector.

16. The ophthalmological system of claim 14, wherein:

the first set of M positions includes (i) a first position with a center located along a first radial vector measured from the center of the pupil toward the outer circumference of the iris and (ii) a second position, adjacent to the first position among the first set of M positions, located along a second radial vector measured from the center of the pupil toward the outer circumference of the iris;

the second set of P positions includes (i) a third position along a third radial vector and (ii) a fourth position adjacent to the third position along the fourth radial vector;

the third radial vector is located between the first radial vector and the second radial vector; and

the second radial vector is located between the third radial vector and the fourth radial vector.

17. The ophthalmological system of claim 14, wherein the first predetermined distance has a value between 0.75 millimeters and 1.5 millimeters, the second predetermined distance has a value between 0 and 1.5 millimeters, and M and P are positive integers of values between 4 and 20.

20. The ophthalmological system of claim 12, wherein the laser illumination light beam comprises laser light of wavelength between 532 nanometers and 1100 nanometers.

21. The ophthalmological system of claim 12, wherein the laser illumination light beam comprises laser light of wavelength between 900 nanometers and 1064 nanometers.

22. The ophthalmological system of claim 12, wherein the laser is a pulse laser and the laser illumination light beam comprises a laser peak power of between 0.5 Watt and 6 Watts.

23. The ophthalmological system of claim 12, wherein the average number of laser shots delivered on the iris of the patient is between 100 and 1000.

24. The ophthalmological system of claim 12, wherein the average number of laser shots delivered on the iris of the patient is between 200 and 300.

18. A non-transitory computer readable storage medium storing one or more programs configured for execution by a computer, the one or more programs comprising instructions to:

obtain a predetermined pattern characterized by a plurality of positions along an iris dilator muscle tissue of an eye of a patient;

align a laser illumination light beam in accordance with one or more of the plurality of positions along the iris dilator muscle tissue, wherein the laser illumination light beam comprises a sequence of light pulses of average time duration between 10 milliseconds and 100 milliseconds;

deliver said laser illumination light beam in the predetermined pattern on a surface of the eye of the patient to target the iris dilator muscle tissue; and

cauterize at least a subset of the iris dilator muscle tissue to weaken dilator muscle, by the delivery of the laser illumination light beam in the predetermined pattern, thereby resulting in a permanently decrease in diameter of the pupil of the eye.

19. A method of improving vision performed using an ophthalmological laser system, the method comprising:

obtaining a predetermined pattern characterized by a plurality of positions along an iris dilator muscle tissue of an eye of a patient;

aligning a laser illumination light beam in accordance with one or more of the plurality of positions along the iris dilator muscle tissue, wherein the laser illumination light beam comprises a sequence of light pulses of average time duration between 10 milliseconds and 100 milliseconds;

delivering said laser illumination light beam in the predetermined pattern on a surface of the eye of the patient to target the iris dilator muscle tissue; and

cauterizing at least a subset of the iris dilator muscle tissue to weaken dilator muscle, by the delivery of the laser illumination light beam in the predetermined pattern, thereby resulting in a permanent decrease in diameter of the pupil of the eye.