Method and apparatus for demodulating signals in a pulse oximetry system

• US 9,351,673 B2
• Filed: 05/05/2014
• Issued: 05/31/2016
• Est. Priority Date: 04/14/1997
• Status: Expired due to Fees

• Current Assignee: Masimo Corporation
• Original Assignee: Masimo Corporation
• Inventors: Diab, Mohamed K., Weber, Walter M., Al-Ali, Ammar
• Primary Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US14/269,606
• Publication Number:
  US 20140243627A1
• Time in Patent Office: 757 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0242 adapted to measure environmental factors, e.g. temperature, pollution
• CPC Class Codes: A61B 2562/0238 Optical sensor arrangements for performing transmission measurements on body tissue
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7217 of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
• CPC Class Codes: A61B 5/7228 Signal modulation applied to the input signal sent to patient or subject; demodulation to recover the physiological signal modulation H03C
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period
• CPC Class Codes: H04J 14/08 Time-division multiplex systems
• CPC Class Codes: H04J 3/10 Arrangements for reducing cross-talk between channels

Abstract

A method and an apparatus measure blood oxygenation in a subject. A light source is activated to cause a first emission at a first wavelength and a second emission at a second wavelength. A detector detects a composite signal indicative of an attenuation of the first and second wavelengths by tissue of a patient. The composite signal is demodulated into a first intensity signal and a second intensity signal. Blood oxygenation in the subject is determined from the first and second intensity signals.

Claims

1. A pulse oximeter configured to measure one or more physiological characteristics of a living subject non-invasively by measuring pulsing light of two or more wavelengths after attenuation by body tissue, the pulse oximeter comprising:

at least one emitter configured to emit light of at least two or more different wavelengths using a modulation scheme that cycles the at least two or more different wavelengths;

at least one detector configured to detect the light of the at least two or more different wavelengths emitted from the at least one emitter after the light has been attenuated by tissue of the living subject, the detector further configured to generate a detector signal representative of the emitted light;

at least one demodulation system configured to demodulate the detector signal and to generate a demodulated detector signal;

an adaptive algorithm processor configured to;

receive one or more inputs;

based, at least in part, on the one or more inputs, generate at least one control signal configured to reduce crosstalk; and

transmit at least one of the control signals to each of the demodulation systems;

wherein each of the demodulation systems is configured to adjust its demodulation based on the at least one control signal to reduce crosstalk;

at least one signal processor configured to use the demodulated detector signal to determine and display at least one physiological measurement; and

the one or more inputs to the adaptive algorithm processor include at least one of;

detector configuration data, calibration data, or a noise demodulated signal.

2. The pulse oximeter of claim 1, wherein the at least one demodulation system is further configured to adjust the at least one demodulation in accordance with the control siganal during a period where one or more of the at least two different wavelengths is turned off.

3. The pulse oximeter of claim 1, wherein the at least one demodulation system is further configured to adjust in accordance with the control siganal during an initial calibration period.

4. The pulse oximeter of claim 3, wherein the adaptive algorithm processor is further configured to adjust the at least one demodulation system in accordance with the control siganal during periodic calibration periods during measurement.

5. The pulse oximeter of claim 1, wherein the at least one demodulation system is further configured to utilize a plurality of demodulation coefficients to demodulate the detector signal.

6. The pulse oximeter of claim 5, wherein the at least one demodulation system is further configured to use at least one demodulation coefficient to demodulate each of the at least two or more different wavelengths.

7. The pulse oximeter of claim 1, wherein the at least one demodulation system is configured to use diagonalization.

8. A method of demodulating a composite signal generated by applying at least first and second periodic pulses of electromagnetic energy to a system having a physiological parameter to be measured and by non-invasively receiving signals responsive to the electromagnetic energy after attenuation by body tissue of a living subject, the signals received as a composite signal having at least first and second components responsive to the at least first and second pulses respectively, said method comprising:

receiving, at one or more signal processors, a composite signal responsive to electromagnetic energy of at least first and second periodic pulses of electromagnetic energy after attenuation by body tissue;

applying, using the one or more signal processors, a first demodulation scheme to the composite signal to generate at least a first demodulated signal;

generating, by an adaptive algorithm, at least one control signal;

automatically adjusting, using the one or more signal processors, the first demodulation scheme based, at least in part, by the at least one control signal;

using at least a second demodulated signal, obtained using the adjusted first demodulation scheme, to determine and display a physiological measurement; and

wherein the adaptive algorithm uses at least one of;

detector configuration data, calibration data, or a noise demodulated signal to generate the control signal.

9. The method of claim 8, wherein the signal processor is further configured to adjust in order to reduce crosstalk.

10. The method of claim 8, further comprising applying a second demodulation scheme to the composite signal to generate a second demodulated signal and adjusting the second demodulation scheme based at least in part on the second demodulated signal.

11. The method of claim 10, wherein the signal processor is further configured to adjust at least one of the first and second demodulation schemes in the absence of at least one of the first and second periodic pulses of electromagnetic energy.

12. The method of claim 10, wherein the signal processor is further configured to adjust at least one of the first and second demodulation schemes based on the demodulated signals in order to further reduce crosstalk interspersed with measurements.

13. The method of claim 8, wherein the signal processor is further configured to adjust continuously.

14. A pulse oximeter for demodulating a composite signal generated by applying at least first and second periodic pulses of electromagnetic energy to a system having a physiological parameter to be measured and by non-invasively receiving signals responsive to the electromagnetic energy after attenuation by body tissue of a living subject, the signals received as a composite signal having at least first and second components responsive to the at least first and second pulses respectively, said pulse oximeter comprising:

means for receiving a composite signal responsive to electromagnetic energy of at least first and second periodic pulses of electromagnetic energy after attenuation by body tissue;

means for applying a first demodulation scheme to said composite signal to generate at least a first demodulated signal;

means for generating, by an adaptive algorithm, at least one control signal, the at least one control signal based at least in part on at least one of;

detector configuration data, calibration data, or a noise demodulated signal;

means for automatically adjusting the first demodulation scheme by the at least one control signal;

means for determining a physiological measurement using a second demodulated signal obtained after adjusting the first demodulation scheme; and

means for displaying the physiological mesaurement.

15. The pulse oximeter of claim 14, further comprising applying a second demodulation scheme to the composite signal to generate a second demodulated signal and adjusting the second demodulation scheme based at least in part on the second demodulated signal.

16. The pulse oximeter of claim 15, wherein the means for automatically adjusting is further configured to adjust at least one of the first and second demodulation schemes in the absence of at least one of the first and second periodic pulses of electromagnetic energy.