Analyte sensor with increased reference capacity

  • US 9,351,677 B2
  • Filed: 03/04/2013
  • Issued: 05/31/2016
  • Est. Priority Date: 07/02/2009
  • Status: Active Grant
First Claim
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1. An implantable electrochemical sensor for measuring an analyte concentration in a host, comprising:

  • a working electrode configured to measure a concentration of an analyte; and

    a silver/silver chloride reference electrode, wherein at least a portion of the silver/silver chloride reference electrode is covered with an enzyme layer, wherein the enzyme layer is configured, in vivo, to generate hydrogen peroxide upon exposure to a substrate, whereby the hydrogen peroxide regenerates silver chloride of the reference electrode such that a reference capacity of the reference electrode is increased.

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