Method and system for dynamically updating calibration parameters for an analyte sensor

• US 9,357,959 B2
• Filed: 08/19/2013
• Issued: 06/07/2016
• Est. Priority Date: 10/02/2006
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Hayter, Gary Alan, Budiman, Erwin Satrya, Doniger, Kenneth J., Mazza, John Charles
• Primary Examiner(s): JANG, CHRISTIAN YONGKYUN
• Application Number:
  US13/970,464
• Publication Number:
  US 20130338454A1
• Time in Patent Office: 1,023 Days
• Field of Search: 600/309, 600/316, 600345-347, 600/365, 345/4, 345/14, 346/68, 422/50, 422402-429, 20440301-40315, 702/23, 604 64- 66
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/0015 characterised by features of the telemetry system
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence

Abstract

Methods and apparatuses including determining a calibration parameter associated with a detected analyte value, calibrating the analyte value based on the calibration parameter, and dynamically updating the calibration parameter are disclosed. Also provided are systems, kits, and computer program products.

Claims

1. A computer implemented method, comprising:

updating, using a processor, a previously determined rate of change of analyte sensor data based on a first analyte sensor data and a previously received analyte sensor data;

performing, using the processor, a lag compensation of the previously received analyte sensor data based on the updated previously determined rate of change of analyte sensor data to generate a lag compensated previously received analyte sensor data; and

controlling administration of therapy based on the lag compensation.

2. The method of claim 1, further including receiving the first analyte sensor data at a first predetermined time period from an analyte sensor.

3. The method of claim 1, further including retrieving, using the processor, the previously determined rate of change of analyte sensor data from a storage device, wherein the previously determined rate of change of analyte sensor data is based on the previously received analyte sensor data.

4. The method of claim 1, further comprising updating a previously determined calibration parameter based on the lag compensated previously received analyte sensor data.

5. The method of claim 4, wherein the calibration parameter is the sensitivity of an analyte sensor.

6. The method of claim 4, further comprising calibrating the first analyte sensor data using the updated previously determined calibration parameter.

7. The method of claim 4, further comprising determining a first rate of change of the first analyte sensor data at a first predetermined time period.

8. The method of claim 7, further comprising performing a lag compensation of the first analyte sensor data based on the first rate of change of the first analyte sensor data to generate a lag compensated first analyte sensor data.

9. The method of claim 8, further comprising calibrating the lag compensated first analyte sensor data using the updated previously determined calibration parameter.

10. An apparatus, comprising;

one or more processing units; and

a memory storing instructions which, when executed by the one or more processing units, causes the one or more processing units to update a previously determined rate of change of analyte sensor data based on a first analyte sensor data and a previously received analyte sensor data, perform a lag compensation of the previously received analyte sensor data based on the updated previously determined rate of change of analyte sensor data to generate a lag compensated previously received analyte sensor data, and control administration of therapy based on the lag compensation.

11. The apparatus of claim 10, wherein the memory further stores instructions which, when executed by the one or more processing units, causes the one or more processing units to receive the first analyte sensor data at a first predetermined time period from an analyte sensor.

12. The apparatus of claim 11, wherein the memory further stores instructions which, when executed by the one or more processing units, causes the one or more processing units to determine a first rate of change of the first analyte sensor data at the first predetermined time period.

13. The apparatus of claim 12, wherein the memory further stores instructions which, when executed by the one or more processing units, causes the one or more processing units to perform a lag compensation of the first analyte sensor data based on the first rate of change of the first analyte sensor data to generate a lag compensated first analyte sensor data.

14. The apparatus of claim 13, wherein the memory further stores instructions which, when executed by the one or more processing units, causes the one or more processing units to calibrate the lag compensated first analyte sensor data using an updated previously determined calibration parameter.

15. The apparatus of claim 10, wherein the memory further stores instructions which, when executed by the one or more processing units, causes the one or more processing units to retrieve the previously determined rate of change of analyte sensor data from the memory, wherein the previously determined rate of change of analyte sensor data is based on the previously received analyte sensor data.

16. The apparatus of claim 10, wherein the memory further stores instructions which, when executed by the one or more processing units, causes the one or more processing units to update a previously determined calibration parameter based on the lag compensated previously received analyte sensor data.

17. The apparatus of claim 16, wherein the calibration parameter is the sensitivity of an analyte sensor.

18. The apparatus of claim 16, wherein the memory further stores instructions which, when executed by the one or more processing units, causes the one or more processing units to calibrate the first analyte sensor data using the updated previously determined calibration parameter.