Treatment of pain with topical diclofenac

  • US 9,375,412 B2
  • Filed: 07/27/2015
  • Issued: 06/28/2016
  • Est. Priority Date: 03/31/2009
  • Status: Active Grant
First Claim
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1. A method for applying topical agents to a knee of a patient with pain, said method comprising:

  • applying a first medication consisting of a topical diclofenac preparation to an area of the knee of said patient to treat osteoarthritis of the knee of said patient, wherein the topical diclofenac preparation consists essentially of 2% w/w diclofenac sodium;

    about 40% to about 50% w/w dimethyl sulfoxide;

    about 23-29% w/w ethanol;

    about 10-12% w/w propylene glycol;

    about 0-6% w/w hydroxypropylcellulose; and

    water to make 100% w/w; and

    wherein the topical diclofenac preparation has a viscosity of 500-5000 centipoise;

    waiting for the treated area to dry;

    subsequently applying a sunscreen, or an insect repellant to said treated area after said treated area is dry, wherein said step of applying a first medication does not enhance the systemic absorption of the subsequently applied sunscreen, or insect repellant;

    wherein said subsequent application occurs during a course of treatment of said patient in which said topical diclofenac preparation is administered twice daily; and

    counseling said patient to avoid taking unprescribed acetaminophen while using said topical diclofenac preparation.

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