Devices and methods for treatment of the aortic arch

• US 9,402,751 B2
• Filed: 02/25/2014
• Issued: 08/02/2016
• Est. Priority Date: 03/13/2013
• Status: Active Grant

• Current Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Original Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Inventors: Zukowski, Stanislaw L.
• Primary Examiner(s): Gherbi, Suzette J
• Application Number:
  US14/189,814
• Publication Number:
  US 20140316514A1
• Time in Patent Office: 889 Days
• Field of Search: 623 131- 135
• US Class Current: 1/1
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/006 modular
• CPC Class Codes: A61F 2250/0065 telescopic

Abstract

The present disclosure includes an endoprosthesis comprising a descending stent-graft, an ascending stent-graft, and/or a side-branch stent-graft. In various embodiments, an ascending stent-graft is capable of being coupled to a descending stent-graft, and/or a descending stent-graft can comprise a fenestration capable of being coupled to a side-branch stent-graft. In addition, in various embodiments, a descending and/or ascending stent-graft can comprise a reduced diameter portion that, when implanted within an aortic arch, recedes from a luminal surface of the aortic arch to allow a side-branch stent-graft to be maneuvered within the aortic arch.

Claims

1. An endoprosthetic assembly for treating a main vessel and at least one branch vessel extending from the main vessel, the endoprosthetic assembly comprising:

a first expandable device and a second expandable device, each having a generally tubular shaped wall comprising a trunk portion configured for engaging the main vessel;

reduced diameter portions of each of the first and second devices having reduced diameters relative to their respective trunk portions, at least one of the reduced diameter portions being concentrically offset from a trunk portion to which it is coupled, and the first and second devices being configured to engage each other telescopically; and

at least one branch for treating the at least one branch vessel and extending through a fenestration in one of the reduced diameter portions.

2. The endoprosthetic assembly as in claim 1 including a second branch through a second fenestration formed in the reduced diameter portion of the other of the first and second expandable devices.

3. The endoprosthetic assembly as in claim 2 including a third branch through a third fenestration formed in the reduced diameter portion of one of the first and second expandable devices.

4. The endoprosthetic assembly as in claim 1 including visually distinct radiopaque or echogenic markers on each of the first and second expandable devices.

5. An endoprosthesis comprising:

a descending stent-graft;

an ascending stent-graft; and

a side-branch stent-graft, the descending stent-graft comprising a reduced diameter portion that, when implanted within an aortic arch, recedes from a luminal surface of the aortic arch to allow the side-branch stent-graft to be maneuvered within the aortic arch.

6. The endoprosthesis of claim 5, wherein the ascending stent-graft is capable of being coupled to the descending stent-graft.

7. The endoprosthesis of claim 5, wherein the descending stent-graft comprises a fenestration capable of being coupled to the side-branch stent-graft.

8. The endoprosthesis of claim 5, wherein the descending stent-graft comprises two fenestrations, a first fenestration capable of being coupled to the side-branch stent-graft and a second fenestration capable of being coupled to another side-branch stent-graft.

9. The endoprosthesis of claim 5, wherein the ascending stent-graft comprises a fenestration capable of being coupled to the side-branch stent-graft.

10. The endoprosthesis of claim 5, wherein the ascending stent-graft comprises a reduced diameter portion that, when implanted within an aortic arch, recedes from a luminal surface of the aortic arch to allow a side-branch stent-graft to be maneuvered within the aortic arch.

11. The endoprosthesis of claim 5, wherein each of the ascending and descending stent-grafts comprises a trunk portion and a reduced diameter portion, the reduced diameter portion coupled to the trunk portion and concentrically offset from the trunk portion.

12. A method comprising:

precannulating a side-branch artery with a guidewire prior to deploying a descending stent-graft, wherein the guidewire abuts a luminal surface of the side-branch artery to facilitate deployment of the descending stent-graft;

deploying the descending stent-graft within the descending portion of an aortic arch;

deploying an ascending stent-graft within an ascending portion of the aortic arch; and

deploying a side-branch stent-graft through a fenestration in one of the ascending stent-graft and the descending stent-graft.

13. The method of claim 12, wherein the ascending stent-graft couples to the descending stent-graft during deployment.

14. The method of claim 12, further comprising maneuvering the side-branch stent-graft within the aortic arch between the fenestration and an ostium of a side-branch artery.

15. The method of claim 12, further comprising deploying two side-branch stent-grafts through two fenestrations in the descending stent-graft and a single side-branch stent-graft through a fenestration in the ascending stent-graft.

16. The method of claim 12, further comprising precannulating the aortic arch with two guidewires prior to the deploying the descending stent-graft.

17. The method of claim 16, wherein the two guidewires extend through common entry into a femoral artery.

18. The method of claim 12, further comprising loading the ascending stent-graft on a guidewire such that a trunk portion of the ascending-stent-graft is located distal to a reduced diameter portion of the ascending stent-graft.

19. The method of claim 12, further comprising imaging one of the descending stent-graft, the ascending stent-graft and the side-branch stent-graft by way of a radiopaque marker.

20. The method of claim 12, wherein a flow through at least one side-branch stent-graft is retrograde relative to a main vessel flow.

21. The method of claim 12, further comprising deploying a balloon in one of the two side-branch stent-grafts.

22. The method of claim 12, the descending stent-graft comprising a trunk portion and a reduced diameter portion, the reduced diameter portion concentrically offset from the trunk portion.

23. The method of claim 12, the ascending stent-graft comprising a trunk portion and a reduced diameter portion, the reduced diameter portion concentrically offset from the trunk portion.

24. An endoprosthesis comprising:

a descending stent-graft;

an ascending stent-graft; and

a side-branch stent-graft, the ascending stent-graft comprising a reduced diameter portion that, when implanted within an aortic arch, recedes from a luminal surface of the aortic arch to allow the side-branch stent-graft to be maneuvered within the aortic arch.

25. An endoprosthesis comprising:

a descending stent-graft;

an ascending stent-graft; and

a side-branch stent-graft, each of the ascending and descending stent-grafts comprising a trunk portion and a reduced diameter portion, the reduced diameter portion coupled to the trunk portion and concentrically offset from the trunk portion.

26. The endoprosthesis of claim 25, wherein the reduced diameter portions of each of the ascending and descending stent-grafts comprises a plurality of alternating first and second stent-rings, wherein the first stent-rings have a first diameter and the second stent-rings have a second diameter different than the first diameter.

27. A method comprising:

precannulating an aortic arch of a patient with two guidewires prior to deploying a descending stent-graft;

deploying the descending stent-graft within a descending portion of the aortic arch;

deploying an ascending stent-graft within an ascending portion of the aortic arch; and

deploying a side-branch stent-graft through a fenestration in one of the ascending stent-graft and the descending stent-graft.

28. A method comprising:

deploying a descending stent-graft within a descending portion of an aortic arch, the descending stent-graft comprising a trunk portion and a reduced diameter portion, the reduced diameter portion concentrically offset from the trunk portion;

deploying an ascending stent-graft within an ascending portion of the aortic arch; and

deploying a side-branch stent-graft through a fenestration in one of the ascending stent-graft and the descending stent-graft.

29. A method comprising:

deploying a descending stent-graft within a descending portion of an aortic arch;

deploying an ascending stent-graft within an ascending portion of the aortic arch, the ascending stent-graft comprising a trunk portion and a reduced diameter portion, the reduced diameter portion concentrically offset from the trunk portion; and

deploying a side-branch stent-graft through a fenestration in one of the ascending stent-graft and the descending stent-graft.