Posture dependent time series filtering system and methods for the detection of cardiac events

• US 9,414,757 B2
• Filed: 11/18/2015
• Issued: 08/16/2016
• Est. Priority Date: 08/12/2009
• Status: Active Grant

• Current Assignee: Angel Medical Systems, Inc.
• Original Assignee: Angel Medical Systems, Inc.
• Inventors: Hopenfeld, Bruce
• Primary Examiner(s): Voorhees, Catherine
• Assistant Examiner(s): Dinga, Roland
• Application Number:
  US14/944,753
• Publication Number:
  US 20160066807A1
• Time in Patent Office: 272 Days
• Field of Search: 600/508, 600/509, 600/515
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/366 Detecting abnormal QRS complex, e.g. widening

Abstract

A device for detecting a cardiac event is disclosed. Detection of an event is based on a test applied to a parameter whose value varies according to heart rate. Both the parameter value and heart rate (RR interval) values are filtered with an exponential average filter. The filtered parameter value and heart rate values are stored as separate datasets corresponding to particular body postures. Upper and lower boundary values and detection thresholds of the parameter are computed for each of the datasets. The test to detect the cardiac event depends on the heart rate and the difference between the parameter'"'"'s value and a corresponding detection threshold.

Claims

1. A cardiac event detection system for detecting a cardiac event in a patient comprising:

(a) at least two sensors for sensing an analog signal from said patient'"'"'s heart;

(b) a device coupled to said sensors, said device having an analog-to-digital circuit system contained therein for digitizing said electrical signal to produce a digitized waveform of a heart rate of said patient over a plurality of heart beats, said heart rate defining a first parameter;

(c) a processor electrically coupled to said analog-to-digital circuit system, said processor configured to;

(i) for each of a plurality of body positions, computing both heart rate time series data and time series data for a second parameter value from the digitized waveform over said plurality of heart beats, thereby generating a plurality of datasets for each of the plurality of postures;

(ii) for each of the plurality of datasets, reducing the dispersion of said second parameter value data as a function of heart rate, thereby generating a plurality of reduced dispersion datasets;

(iii) for each of the plurality of reduced dispersion datasets, generating upper and lower normal boundaries of the value of the second parameter as a function of heart rate;

(iv) for each of the plurality of reduced dispersion datasets, generating upper and lower detection thresholds from the upper and lower normal boundaries;

(v) perform a cardiac event detection test that involves comparing a value of the second parameter of at least one beat with its associated posture dependent upper or lower detection threshold.

2. The system of claim 1 wherein the processor reduces the dispersion by low pass filtering the heart rate time series data.

3. The system of claim 1 wherein the processor reduces the dispersion by low pass filtering the second parameter time series data.

4. The system of claim 1 wherein the processor reduces the dispersion by excluding outlier second parameter values from the plurality of reduced dispersion datasets.

5. The system of claim 1 wherein the second parameter is ST segment deviation.