Treating pain in patients with hepatic impairment

CAFC
  • US 9,421,200 B1
  • Filed: 05/13/2016
  • Issued: 08/23/2016
  • Est. Priority Date: 07/31/2012
  • Status: Active Grant
First Claim
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1. A method of treating pain in a patient having mild or moderate hepatic impairment, the method comprising:

  • administering to the patient having mild or moderate hepatic impairment an oral dosage unit having hydrocodone bitartrate as the only active ingredient, wherein the dosage unit comprises an extended release formulation of hydrocodone bitartrate, wherein the dose is not adjusted for the patient having mild or moderate hepatic impairment and wherein the dosage unit provides a plasma half-life of hydrocodone of about 8 hours in patients without hepatic impairment.

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