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Methods for making an aqueous radiation protecting formulation

  • US 9,421,287 B2
  • Filed: 03/05/2015
  • Issued: 08/23/2016
  • Est. Priority Date: 11/17/2011
  • Status: Active Grant
First Claim
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1. A method of inhibiting damage to a saccharide sensor that can result from a radiation sterilization process, the method comprising combining the saccharide sensor with an aqueous radioprotectant formulation during the sterilization process, wherein:

  • the saccharide sensor comprises a saccharide binding polypeptide;

    the aqueous radioprotectant formulation comprises an antioxidant compound; and

    performing the sterilization process under conditions wherein the antioxidant reacts with a free radical compound produced during the radiation sterilization process, wherein the free radical compound can react with and damage the saccharide binding polypeptide.

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