Dosing regimen associated with long acting injectable paliperidone esters

  • US 9,439,906 B2
  • Filed: 12/17/2008
  • Issued: 09/13/2016
  • Est. Priority Date: 12/19/2007
  • Status: Active Grant
First Claim
Patent Images

1. A dosing regimen for administering paliperidone palmitate to a psychiatric patient in need of treatment for schizophrenia, schizoaffective disorder, or schizophreniform disorder comprising(1) administering intramuscularly in the deltoid of a patient in need of treatment a first loading dose of about 150 mg-eq. of paliperidone as paliperidone palmitate formulated in a sustained release formulation on the first day of treatment;

  • (2) administering intramuscularly in the deltoid muscle of the patient in need of treatment a second loading dose of about 100 mg-eq. of paliperidone as paliperidone palmitate formulated in a sustained release formulation on the 6th to about 10th day of treatment; and

    (3) administering intramuscularly in the deltoid or gluteal muscle of the patient in need of treatment a first maintenance dose of about 25 mg-eq. to about 150 mg-eq. of paliperidone as paliperidone palmitate in a sustained release formulation a month (±

    7 days) after the second loading dose.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×