Sensor
First Claim
Patent Images
1. A sensor for detecting and/or quantifying the amount of analyte in a sample, the sensor comprising:
- a sensing region; and
a barrier layer comprising a reactive oxygen species (ROS)-quenching, analyte-permeable membrane having an ROS-quenching agent within pores of the membrane, the pores each having a length, wherein the ROS-quenching agent is distributed along the length of the pores; and
wherein the sensor is configured so that the sample enters the sensing region of the sensor through said barrier layer.
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Abstract
A sensor for detecting and/or quantifying the amount of analyte in a sample, the sensor including:
- a sensing region; and
- a barrier layer including a reactive oxygen species (ROS)-quenching, analyte-permeable membrane having an ROS-quenching agent adsorbed thereto;
wherein the sensor is adapted so that the sample enters the sensing region of the sensor through said barrier layer.
18 Citations
18 Claims
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1. A sensor for detecting and/or quantifying the amount of analyte in a sample, the sensor comprising:
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a sensing region; and a barrier layer comprising a reactive oxygen species (ROS)-quenching, analyte-permeable membrane having an ROS-quenching agent within pores of the membrane, the pores each having a length, wherein the ROS-quenching agent is distributed along the length of the pores; and wherein the sensor is configured so that the sample enters the sensing region of the sensor through said barrier layer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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- 15. A reactive oxygen species (ROS)-quenching, analyte-permeable membrane having pores, configured for use in a sensor for detecting and/or quantifying the amount of analyte in a sample, the membrane having an ROS-quenching agent within the pores of the membrane, wherein each pore of the membrane has a length and the ROS-quenching agent is distributed along the length of the pores.
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18. A method of detecting and/or quantifying the amount of analyte in a sample, comprising inserting into the sample a sensor, providing incident light to a sensing region of the sensor and detecting an emission pattern of a fluorophore;
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wherein the sensor is configured for detecting and/or quantifying the amount of analyte in a sample and comprises; a sensing region; and a barrier layer comprising a reactive oxygen species (ROS)-quenching, analyte-permeable membrane having an ROS-quenching agent within pores of the membrane, each pore of the membrane has a length and the ROS-quenching agent is distributed along the length of the pores; wherein the sensor is configured so that the sample enters the sensing region of the sensor through said barrier layer.
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Specification