Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof

  • US 9,492,559 B2
  • Filed: 01/15/2015
  • Issued: 11/15/2016
  • Est. Priority Date: 01/21/2014
  • Status: Active Grant
First Claim
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1. An immunogenic composition comprising a Streptococcus pneumoniae serotype 22F glycoconjugate, wherein the glycoconjugate has a molecular weight of between 1000 kDa and 12,500 kDa and comprises an isolated capsular polysaccharide from S. pneumoniae serotype 22F and a carrier protein, and wherein a ratio (w/w) of the polysaccharide to the carrier protein is between 0.4 and 2.

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