Syringe for the delivery of viscous compositions

• US 9,539,042 B2
• Filed: 03/28/2008
• Issued: 01/10/2017
• Est. Priority Date: 03/30/2007
• Status: Active Grant

• Current Assignee: Stryker Corporation
• Original Assignee: Orthovita Inc. (Stryker Corporation)
• Inventors: Paris, Michael W., Clineff, Theodore D., Entrekin, Dean A., Bagga, Charanpreet S., Murphy, James P.
• Primary Examiner(s): PELLEGRINO, BRIAN E
• Application Number:
  US12/057,603
• Publication Number:
  US 20080243130A1
• Time in Patent Office: 3,210 Days
• Field of Search: 604/64, 604/187, 604/188, 604/218, 604/220, 604/224, 606/92, 606/93, 606/94
• US Class Current: 1/1
• CPC Class Codes: A61B 17/8822 characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum
• CPC Class Codes: A61B 17/8825 characterised by syringe details A61B17/8822, A61B17/8827 take precedence
• CPC Class Codes: A61B 17/8827 with filtering, degassing, venting or pressure relief means

Abstract

A syringe configured to deliver viscous compositions is described, in which the syringe may include an elongate chamber having side port(s) extending therefrom. Various viscous compositions may be inserted through the side port(s) and into the elongate chamber, which may further house a plunger for ejecting the composition. One portion of the plunger may interact with a restricted opening on the chamber to inhibit removal of the plunger from the chamber; and another portion of the plunger may have a locking structure, which cooperates with a locking structure on the chamber to selectively fix the plunger with respect to the chamber. The plunger may also be fully slidable within the chamber when the locking structures of the plunger and the elongate chamber are not engaged. Related methods of using the aforementioned syringe, as well as kits including further instruments that interact with the syringe, are also disclosed.

Claims

1. A device for the delivery of a composition, the device comprising:

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening, the cap covering at least a portion of the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber; and

(d) a plunger having a plunger seal slidable in sealing engagement within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction;

(e) the plunger having an interference member that inhibits removal of the plunger from the elongate chamber through the restricted opening; and

(f) the elongate chamber having a locking structure that is engageable and disengageable with a corresponding locking structure on the plunger, wherein engagement between the locking structures of the elongate chamber and the plunger locks the plunger and its plunger seal relative to the elongate chamber, and disengagement between the locking structures of the elongate chamber and the plunger unlocks the plunger and its plunger seal relative to the elongate chamber so that the plunger and its plunger seal are movable within the elongate chamber.

2. The device of claim 1, wherein the axes of the lumens of the chamber and side port form an angle of about 60 degrees to 75 degrees.

3. The device of claim 1, wherein the axes of the lumens of the chamber and side port form an angle of about 45 degrees.

4. The device of claim 1, wherein the engaging and disengaging results from rotation of the plunger around a longitudinal axis of the plunger.

5. The device of claim 1, wherein the engaging maintains a distal end of the plunger at the position proximal to conjunction of the lumens.

6. The device of claim 1, wherein the side port further comprises a flow regulation element.

7. The device of claim 1, wherein the side port is detachable from the chamber.

8. The device of claim 1, wherein the side port further comprises at least one filter element.

9. The device of claim 1, wherein the chamber is comprised of a translucent or a transparent material.

10. The device of claim 1, wherein the chamber further comprises an indicator for assessing the contents of the chamber.

11. The device of claim 1, wherein at least one of the elongate chamber, plunger, and side port are comprised of generally flexible material.

12. The device of claim 1, wherein the chamber and the plunger further comprise handles.

13. The device of claim 1, wherein a composition inserted into the elongate chamber includes a viscosity that is between 100 centipoise and 400,000 centipoise.

14. The device of claim 1, wherein a composition inserted into the elongate chamber includes a viscosity that is between 150,000 centipoise and 400,000 centipoise.

15. The device of claim 1 comprising two side ports.

16. The device of claim 1, further comprising at least one cannula or catheter.

17. The device of claim 16, wherein the cannula or catheter is fixably attached to the elongate chamber.

18. The device of claim 1, wherein the plunger comprises a lumen.

19. The device of claim 18, further comprising a penetrable barrier within the plunger lumen.

20. The device of claim 18, further comprising a plunger insert.

21. A device for the delivery of a composition, the device comprising:

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening, the cap covering at least a portion of the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber;

(d) a plunger having a plunger seal slidable in sealing engagement within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction;

(e) a locking structure on the elongate chamber that is engageable and disengageable with a corresponding locking structure on the plunger, wherein engagement between the locking structures of the elongate chamber and the plunger locks the plunger and its plunger seal relative to the elongate chamber in a locked position, and disengagement between the locking structures of the elongate chamber and the plunger unlocks the plunger and its plunger seal relative to the elongate chamber so that the plunger and its plunger seal are movable within the elongate chamber; and

(f) a rotational element on the plunger which, when the plunger is in the locked position, indicates to a user of the device that the plunger is in the locked position;

(g) the plunger having an interference member that cooperates with the restricted opening to inhibit removal of the plunger from the elongate chamber through the restricted opening.

22. The device of claim 21, wherein the rotational element, when rotated to the locked position, provides tactile or auditory feedback to the user that indicates the plunger is in the locked position.

23. The device of claim 21, wherein a dimensional interference between the rotational element and a portion of the elongate chamber indicates to the user of the device that the plunger is in the locked position.

24. The device of claim 23, wherein the dimensional interference provides both auditory and tactile feedback to the user to indicate that the plunger is in the locked position.

25. A device for the delivery of a composition, the device comprising:

(a) an elongate chamber having a lumen;

(b) a cap on the proximal end of the chamber having a restricted opening, the cap covering at least a portion of the lumen of the chamber;

(c) at least one side port having a lumen, said side port lumen being in fluid communication with the lumen of the elongate chamber; and

(d) a plunger having a plunger seal slidable in sealing engagement within the lumen of the elongate chamber from a position proximal to conjunction of the lumens of the side port and elongate chamber to a position distal to said conjunction;

(e) the elongate chamber having a locking structure that is engageable and disengageable with a corresponding locking structure on the plunger, wherein engagement between the locking structures of the elongate chamber and the plunger locks the plunger and its plunger seal relative to the elongate chamber, and disengagement between the locking structures of the elongate chamber and the plunger unlocks the plunger and its plunger seal relative to the elongate chamber so that the plunger and its plunger seal are movable within the elongate chamber.

26. The device of claim 25, wherein the plunger further comprises an interference member that inhibits removal of the plunger from the elongate chamber.

27. The device of claim 25, wherein the axes of the lumens of the chamber and side port form an angle less than 75 degrees.