System for closed transfer of fluids

• US 9,597,260 B2
• Filed: 03/11/2014
• Issued: 03/21/2017
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Ivosevic, Milan, Marici, Paul Paia
• Primary Examiner(s): Maust, Timothy L
• Assistant Examiner(s): SCHMID, ANDREW C
• Application Number:
  US14/204,428
• Publication Number:
  US 20140261877A1
• Time in Patent Office: 1,106 Days
• Field of Search: 141/27, 141/311.R, 141/312, 141/318, 141/319, 141/321, 141/322, 141/326, 141/329, 141/330, 141/346, 141/351, 141/352, 141/353, 141/357, 141/369, 141/370, 141/372, 141/383, 141/384, 141/385, 141/386, 604/411, 604/415
• US Class Current: 1/1
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2048 Connecting means
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2072 for internal venting
• CPC Class Codes: A61J 1/2082 for gas filtration
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2039/1027 Quick-acting type connectors
• CPC Class Codes: A61M 2039/1044 Verifying the connection, e.g. audible feedback, tactile feedback, visual feedback, using external light sources
• CPC Class Codes: A61M 2039/1072 with a septum present in the connector
• CPC Class Codes: A61M 39/12 for joining a flexible tube to a rigid attachment
• CPC Class Codes: A61M 39/14 for connecting tubes having sealed ends needle sets A61M5/162; having valves closing automatically on disconnection of line A61M39/26
• CPC Class Codes: Y10T 29/49217 by elastic joining

Abstract

A system for the closed transfer of fluids that provides substantially leak-proof sealing and pressure equalization during engagement of a cannula with a vial, during transfer of a substance from a vial chamber to a barrel chamber via the cannula, and during disengagement of the cannula from the vial is disclosed. The leak-proof sealing of the system substantially prevents leakage of both air and liquid during use of the system. The system of the present disclosure also permits pressure equalization between a vial and the system when the system is attached to the vial. The system is compatible with a needle and syringe assembly for accessing a medication contained within a vial for administering the medication to a patient.

Claims

1. A system comprising:

a cannula having a proximal end and a distal end, the cannula attachable to a first container having a first chamber such that the cannula is in fluid communication with the first chamber;

a syringe adapter having a housing and a cannula seal comprising a resilient sleeve, the cannula seal being disposed within the housing and moveable relative to the housing between a sealed position where the distal end of the cannula is enclosed by the cannula seal and a retracted position where the distal end of the cannula is positioned outside of the cannula seal, the housing including a first connection element; and

a second container adapter attachable to a second container having a second chamber, the second container adapter having a second container seal and a second connection element,

wherein with the first connection element of the syringe adapter engaged with the second connection element of the second container adapter, the syringe adapter is secured to the second container adapter, and wherein the cannula seal contacts the second container seal providing a substantially leak-proof seal during engagement of the cannula with the second container, during transfer of a first substance from the second chamber of the second container to the first chamber of the first container via the cannula, and during disengagement of the cannula from the second container.

2. The system of claim 1, wherein the second container adapter comprises a pressure equalization system having a toroidal expandable balloon.

3. The system of claim 2, wherein the second container adapter includes a second container adapter housing and a portion of the toroidal expandable balloon is not covered by the second container adapter housing.

4. The system of claim 2, wherein a portion of the toroidal expandable balloon can expand in an axial direction.

5. The system of claim 1, wherein the syringe adapter includes an intake air filter.

6. The system of claim 1, wherein the first connection element comprises a first projecting element and the second connection element comprises a first connection channel, a first disconnection channel, and a first securement element disposed between the first connection channel and the first disconnection channel, the first connection channel distinct from the first disconnection channel, wherein with the first projecting element engaged with the first securement element, the syringe adapter is secured to the second container adapter.

7. The system of claim 1, wherein the first container is a syringe barrel.

8. The system of claim 1, wherein the second container is a vial.

17. The system of claim 1, further comprising a biasing element in contact with a portion of the housing, the biasing element configured to bias the cannula seal toward the distal end of the cannula.

18. The system of claim 1, wherein the housing of the syringe adapter comprises a first end, a second end, and a sidewall extending between the first end and the second end of the housing of the syringe adapter, the housing of the syringe adapter extending from the proximal end of the cannula to a position past the distal end of the cannula.

9. A system comprising:

a first container defining a first chamber;

a cannula having a proximal end and a distal end, the cannula attachable to the first container such that the cannula is in fluid communication with the first chamber;

a syringe adapter having a housing and a cannula seal comprising a resilient sleeve, the cannula seal being disposed within the housing and moveable relative to the housing between a sealed position where the distal end of the cannula is enclosed by the cannula seal and a retracted position where the distal end of the cannula is positioned outside of the cannula seal, the housing including a first connection element;

a second container defining a second chamber;

a second container septum engaged with the second container to seal the second chamber; and

a second container adapter attachable to the second container, the second container adapter having a second container seal and a second connection element, and

wherein with the first connection element of the syringe adapter engaged with the second connection element of the second container adapter, the syringe adapter is secured to the second container adapter, and wherein the cannula seal contacts the second container seal providing a substantially leak-proof seal during engagement of the cannula with the second container, during transfer of a first substance from the second chamber of the second container to the first chamber of the first container via the cannula, and during disengagement of the cannula from the second container.

10. The system of claim 9, wherein the second container adapter includes a pressure equalization system comprising a toroidal expandable balloon.

11. The system of claim 10, wherein the second container adapter includes a second container adapter housing and a portion of the toroidal expandable balloon is not covered by the second container adapter housing.

12. The system of claim 10, wherein a portion of the toroidal expandable balloon can expand in an axial direction.

13. The system of claim 9, wherein the syringe adapter includes an intake air filter.

14. The system of claim 9, wherein the first connection element comprises a first projecting element and the second connection element comprises a first connection channel, a first disconnection channel, and a first securement element disposed between the first connection channel and the first disconnection channel, the first connection channel distinct from the first disconnection channel, wherein with the first projecting element engaged with the first securement element, the syringe adapter is secured to the second container adapter.

15. The system of claim 9, wherein the first container is a syringe barrel.

16. The system of claim 9, wherein the second container is a vial.