Method for the treatment of Dravet syndrome

  • US 9,603,815 B2
  • Filed: 01/21/2016
  • Issued: 03/28/2017
  • Est. Priority Date: 05/03/2013
  • Status: Active Grant
First Claim
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1. A method of treating seizures in a patient diagnosed with Dravet syndrome, comprising:

  • administering to the patient diagnosed with Dravet Syndrome a therapeutically effective dose of a 5-HT2C agonist;

    administering an effective dose of stiripentol or a pharmaceutically acceptable salt thereof to said patient;

    administering an effective dose of valproate or a pharmaceutically acceptable salt thereof to said patient;

    administering an effective dose of clobazam or a pharmaceutically acceptable salt thereof to said patient; and

    allowing the 5-HT2C agonist to stimulate 5-HT2C receptors in the patient and thereby reduce seizures in the patient, wherein the 5-HT2C agonist is fenfluramine.

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