Devices and methods for treating urological disorders

• US 9,623,253 B2
• Filed: 03/14/2014
• Issued: 04/18/2017
• Est. Priority Date: 07/17/2012
• Status: Active Grant

• Current Assignee: Curonix Company Limited
• Original Assignee: Micron Devices LLC
• Inventors: Perryman, Laura Tyler, Andresen, Chad
• Primary Examiner(s): Wieland, Robert N
• Application Number:
  US14/775,429
• Publication Number:
  US 20160023005A1
• Time in Patent Office: 1,131 Days
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37229 Shape or location of the implanted or external antenna
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

Some implementations provide a method for treating urological disorders in a patient, the method including: placing an introducer into a patient'"'"'s body through an incision site on the patient'"'"'s body, the patient suffering from an urological disorder; placing an implantable wireless device into an inner lumen of the introducer, the implantable wireless device suitable to fit into the inner lumen and configured to receive electromagnetic energy non-inductively from a source located outside the patient'"'"'s body; through the inner lumen of the introducer, positioning the implantable wireless device adjacent to or near one or more excitable tissue in the patient, the one or more excitable tissue regulating a nerve activity associated with the urological disorder; and causing neural modulation of the one or more excitable tissue through one or more electrodes on the implantable wireless device.

Claims

1. A method for treating a urological disorder in a patient, the method comprising:

placing an introducer into a patient'"'"'s body through an incision site on the patient'"'"'s body to access one or more excitable tissue regulating a nerve activity associated with the urological disorder that the patient is suffering from;

placing an implantable wireless device into an inner lumen of the introducer, the implantable wireless device suitable to fit into the inner lumen and configured to receive electromagnetic energy non-inductively from a source located outside the patient'"'"'s body;

through the inner lumen of the introducer, positioning the implantable wireless device adjacent to or near the one or more excitable tissue in the patient; and

causing neural modulation of the one or more excitable tissue through one or more electrodes on the implantable wireless device where electrical stimulation is applied solely using the electromagnetic energy received non-inductively from the source outside the patient'"'"'s body.

2. The method of claim 1, wherein placing the introducer comprises:

placing the introducer through the incision site into a sacral region of the patient.

3. The method of claim 2, wherein positioning the implantable wireless device comprises:

positioning the implantable wireless device adjacent to or near a sacral nerve of the patient.

4. The method of claim 1, wherein placing the introducer comprises placing the introducer through the incision site into a pelvic region of the patient.

5. The method of claim 4, wherein positioning the implantable wireless device comprises positioning the implantable wireless device adjacent to a pudendal nerve or branches thereof.

6. The method of claim 4, wherein positioning the implantable wireless device comprises positioning the implantable wireless device adjacent to or near a prostatic plexus of the patient.

7. The method of claim 4, wherein positioning the implantable wireless device comprises positioning the implantable wireless device adjacent to or near a sacral splanchnic nerve of the patient.

8. The method of claim 4, wherein positioning the implantable wireless device comprises positioning the implantable wireless device adjacent to or near a cavernous nerve of the patient.

9. The method of claim 1, wherein placing the introducer comprises placing the introducer percutaneously through an incision site on the patient'"'"'s lower extremity.

10. The method of claim 9, wherein positioning the implantable wireless device comprises placing the implantable wireless device adjacent to or near a tibial nerve of the patient.

11. The method of claim 1, wherein placing the implantable wireless device further comprises placing the wireless electrode lead into the inner lumen of the introducer having a size of 14 gauge or under.

12. The method of claim 1, further comprising using X-Ray fluoroscopy to guide positioning the wireless electrode lead adjacent to or near one or more excitable tissue.

13. The method of claim 1, further comprising using ultrasound sonography to guide positioning the implantable wireless device adjacent to or near one or more excitable tissue.

14. The method of claim 1, further comprising withdrawing the implantable wireless device from the patient after the neural modulation.

15. The method of claim 1, wherein causing the neural modulation comprises:

causing an input signal to be transmitted from an external antenna outside the patient'"'"'s body, the input signal including electrical power and excitation pulses to drive the one or more electrodes of the implantable wireless device;

causing the input signal to be received non-inductively by one or more antennas on the implantable wireless device;

causing the electrical power and excitation pulses to be extracted from the input signal; and

based on the extracted electrical power, causing the excitation pulses to be delivered to the one or more electrodes on the implantable wireless device.

16. The method of claim 1, wherein placing an implantable wireless device further comprises placing a implantable wireless device that includes (i) one or more non-inductive antennas configured to receive electromagnetic energy radiated from a source located outside of the patient'"'"'s body, (ii) electronic circuitry coupled to each of the one or more non-inductive antennas and configured to extract electric power and excitation pulses from the radiated electromagnetic energy as received by the one or more non-inductive antennas, and (iii) one or more electrodes configured to deliver the excitation pulses to the one or more excitable tissue to effectuate neural modulation thereof.

17. The method of claim 16, wherein placing the implantable wireless device further comprises placing the implantable wireless device that includes at least one of:

a spiral electrode, a cuff electrode, a steroid eluting electrode, a wrap-around electrode, a linear electrode, or a hydrogel electrode.